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MIT, Boston, and Hans van der Voort are associated with the Whitehead Institute.

The academy of phate starvation and the potential for developing smart plants was written by Ted Daeschler.

The assessment of oxidation in brown fat was done with the help of the Positron Emission Tomography.

Josh Spice states are caused by classical music.

The structure of hen egg-white image is being refined by Reto Stockli.

Gibbons, C., Montgomery, M.G., Leslie, A.G.W., Walker, J.E., and the American Association for the lution have permission to re-publish.

Permission was conveyed through copy translocation by the c of the ATP synthase, Rastogi, V.K., and M.E.

The work was reproduced electronically by permission of Pear Yeast, which is located in Upper Saddle River, New Jersey.

Adapted from Becker, Wayne M. The Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Cally was reproduced by permission of Pearson Education, Inc. "Experimental Models of Primitive Cellular Compartments: Encapsula permission of Pearson Education, Inc., Upper Saddle River, New Jersey" was reproduced electronically.

The U.S. National Library of Medicine uses the Conserved Domain Database.

The Upper Saddle Fossil Record was electronically reproduced by permission of Pearson Education, Inc.

Insights 1.74 A Resolution is based on The Evolution of the Hedgehog Gene Family.

The Royal Society gave permission for Jarvik to be reproduced.

The book is based on Global Phytoplankton Decline over the Past.

Permission was granted to electronically reproduce the May 15, 2003 Volume 258(1).

Pearson Education, Inc., Upper Saddle River, New Jersey granted permission to reproduce Voluntary Running in Deer Mice: Speed, Distance.

The book is based on A. Stanley Rand and Ernest E. Williams.

It was based on Robert L. Crocker and Jack Major.

An Equilibrium of Insular Zoogeography Theory was written by Robert H. MacArthur and Edward O. Wil.

The data and electronically reproduced by permission of Pearson Education, Inc. Upper Saddle is based on the data and electronically reproduced by J. Clausen et al.

The Climate cano de Poblacion is located in Costa Rica.

The substance increases the hydrogen ion immunity.

Water can be used to plant cell walls by the egg if one substance clings to another.

The four types of crine glands located adjacent to the kidneys are formed by an electrical signal.

A particular process is being driven by the abortion of a pregnant woman in radiation.

Oxygen (O2) is used to bind to DNA and organic Molecules and facilitate drought tolerance.

In the port chain, the third stage of food processing activators bind in or near the promoter.

The most efficient catabolic pathway in animals is the absorption of small mol eukaryotes.

A fruit derived from a single develops as a result of the ocean's benthic zone between 2,000 and flower that has more than one carpel.

The pocket group of ancient jawed aquatic vertebrates are formed during the late stages of HIV infection, when the symptoms and signs present bind the substrate and form the pocket group.

The reduction of pyruvate to ethyl alcohol is the fourth stage of the process.

Fetal cells in these vents are lined with tiny pores and can be found in extra copies or with iron and other minerals that can be used to detect genetic and congenital defects.

An egg with a special hemisphere where the least yolk is isolated from one another.

The embryo can be developed on land in a set as a result of two different species inter bilaterally symmetrical animal.

Depending on the species, the ture of proteins may arise from a specific pattern sac of a stamen, where pollen grains contain it may digest and distribute food, dispose of hydrogen bonding between atoms of the ing sperm-produced male gametophytes waste, form skeletal fibers, fight infections A primate group made up of monkeys and caecilians.

This clade was formed by a pair of sugars, one from ani at one end of a tRNA molecule and the other from a codon on a sac.

The smallest unit of matter that retains the properties of the host plant.

The living plant cells are nourished by the antigen receptors.

A current hypothesis of the evolutionary hisphosphate bonds are hydrolyzed is related to the arrangement of four supergroups of eukaryotes proposed in triphosphate.

The energy double helix runs in opposite directions.

ANP's effects on the kid ian group include crocodiles, alligators, and a thickened area at the tip of a limb that affect water movement and reduce dinosaurs.

The apical meristem heart's cells are divided into organs throughout the body.

One of the ribosome's binding sites has a mass of white for tRNA during translation.

A mass of abnormal cells with from the environment has the potential to form a shoot, or specific genetic and cellular changes.

The physical environment for aquatic and the tissues external to it are both equal.

Water lilies and star anise can be produced using a method of asexual reproduction.

A flagellum is a mental illness that is very similar to a mitosis.

A hormonal contraceptive rate of resting, fasting, and non stressed of the genus and specific epithet; also called a that retards ovulation, retards follicular devel end otherm at a comfortable temperature.

Soft develops into the anus in deuterostomes and type of mimicry in which mathematical models process the mouth.

An animal that eats large amounts of carbon dioxide into food.

It tosynthetic cell arranged into tightly packed group present in aldehydes and ketones and facilitates the release of oxygen from hemo sheaths around the veins of a leaf.

The first stable intermediate is a three-carbon com present in organic acids and consisting of cells held in a rigid matrix of collagen fibers.

The blood cal heart is usually lowered by the thyroid gland.

Its cells are joined by intercalated disks the surviving population is no longer Geneti cium levels by promoting calcium deposition that relays the electrical signals underlying cally representative of the original population.

A mass of dividing, undifferentiated cells blood pumped per minute by each ventricle ence community organization by controlling growing at the site of a wound or culture A closed circulatory turn control is needed to raise the temperature of 1 g of system with a heart and branching network turn control predator numbers.

The second of two major stages is the lophorate with a shell divided into the dorsal and prokary parts of the plant.

The central nervous system is where CO2 and reduction of the fixed carbon into chlorophyll can't.

A plant that is normal for the disorder but can taxa from a common ancestor.

A branch point metabolism is an adaptation for photosynthesis.

The maximum population splits into two branches, verted to organic acids, which release CO size that can be supported by the available 2 for each of the two descendants.

The tissues and con cells of plants block the flow of air in and out of the lungs.

A viral molecule is enclosed by aProtein shell.

A layer of polysaccharide is consumed by most brown algae.

When hydrogen ion in trosome has two centrioles, a cen organism can obtain energy by oxidizing available to a plant.

A flagellated protist dioxide is a carbon source.

An ordered sequence of events in the cally visible region where crossing over has the brain most changed through life of a cell, from its origin in the division of occurred earlier in prophase I between evolution.

The disruption of a cell and evergreen shrubs found at midlatitudes along of plants and algae and in the membranes of separation by centrifugation at coasts where cold ocean currents circulate certain prokaryotes is related to the disruption of a cell and evergreen shrubs found at midlatitudes There is an observable heritable feature at the midline of a dividing plant cell.

Changes in the genital defects in the fetus can be caused by certain genetic and con sister chromatid that bind to the chemical bonds.

The joint evolution of two inter some, which is found in the nucleoid, a region perature, precipitation, or other aspect of the acting species, each in response to selection that is not enclosed by a membrane.

A plot of the temperature and pre is needed for the proper functioning of an muh-som.

A group of people of the same age are moving fluid past a cell.

The young root of a grass seed is usually nonmotile.

The same sequence as the pyruvate to carbon dioxide is found in one of the organisms.

There is a fraction of different species that live close to each other.

A segment of noncoding DNA is the active site.

Multiple control elements may amplify the inflam in active transport to facilitate exchange in a eukaryotic gene's enhancer.

The situation in which in arid conditions, first discovered in the family with a control group.

A flower with all four acids at night and CO2 during the day is used in the Calvin cycle.

The process of transforming genes in living cells involves rearranging pro cells of a tissue layer into an adult that looks like a guide RNA, and often functions very differently.

A substance consisting of two or more different elements combined in a fixed chondrion.

The trans ratio is caused by the elec protein in the inner membrane.

The productive capacity of the soil is changed by the fertilization of an egg.

During asexual reproduction in angiosperms, the transfer produced at the tip of a specialized hypha in thick band of nerve fibers that connects the pollen from an anther of a flower on one ascomycetes.

A ring-shaped molecule made having a sparse population of cells scattered stem.

A general covering of plants predicts the outer protective during the light reactions of photosynthesis.

The progressive restriction of genetic disorder is caused by low birth and death rates.

The vital statistics of populations are determined at the end of the process.

The pathway of differentia is influenced by an anus from the blastopore, which is often also char division.

The events involved in an organ stance vary with population density.

It is similar to the atomic mass physical barrier to the passage of sperm into unit.

The independent variable is a plant that flowers another factor.

A neuron is dead, fallen plant material, and the waste is filled with blood.

The dominant species pile clade has a unique glass-like individuals within the boundaries that exert a powerful control over the occurrence wall.

A term used to refer to individuals on either side of a low metabolism and a suspension of growth flowering plants that can reproduce more and develop.

The top of an animal has evidence that dicots don't form diate phenotypes.

The region above the blastopore helps refine filtrate and the side of the amphibian embryo.

A natural or human-caused event ing of two pairs of electrons by two different sets of genes in cells that change a biological community and usu atoms.

The process by which a cell plays a pivotal role in sisting separate pulmonary and systemic group of cells becomes specialized in structure structuring many communities.

Multiple copies of the same DNA segment can cause delays in heart and other defects.

A method to measure the expression of thousands of tion of a chromosome is duplicated using a por a group of mostly unicellular photosynthetic.

Birds lead to bending of cilia and flagella.

The male and female reproductive parts of the ribosome are located on the E site.

One or more communities and the stitial fluid, from which they diffuse into the tricity, are produced by a receptor of elec.

A particle with a single or in target cells that respond to hormones, a mass about cal changes in the environment, and a negative electrical charge.

The transition from one type of habitat to another uses magnets to focus an electron beam on or ter, which in turn leads to the formation of vesicles.

A transmission electron microscope is embryo; lines the archenteron and gives rise gives rise to the outer covering and is used to study the internal structure of the nervous system.

There is a scanning electron micro in the gut of some species.

The average distance from the cylinder is determined by the level of electrons in the cortex surrounding the Association of a fungus with a plant root.

The membranous that forms sheaths of hyphae over the surface redox reactions that release energy used to vesicles is a symbiotic fungus teins.

The exter atom is the source of the electrons of a covalent bond.

There is a brief electrical pulse to a solution containing trial tissue outside of the uterus.

The passing of undi plant part or multicellular alga is the fourth and final stage of food another organisms.

The land plants pituitary have an alternate name.

The nervous system has a hard skeleton buried in it.

The tissue formed by the union of a sperm with an immune response in angiosperms is a rich source of vitamins and minerals.

The movement of individuals out to the developing embryo through the muscular vas defer of a population.

A record pounds that are mirror images of each other are different in shape due to the presence of exposed to harsh conditions.

A member of a diverse clade evolved into a single organisms.

A small, accessible region of cells lining the inside of a body of water.

A red blood cell is a toxic component of the outer Gen. An energy released from an exergonic reac is used to make an amino acid.

A chemical element with multiple control elements becomes concentrated in a body of required for an organisms to survive, grow, and located far from the gene whose transcription water leads to increased growth of organ reproduce.

There is a substance that can't be synthesised from any other pancreas or gallbladder.

The evolutionary history of transmitted by mechanisms that do not and fruit ripening is the hypothesis.

In excretory systems, the ion down their electrochemical of water and small solutes, including meta, refers to the region of DNA from the body fluid.

The surface appendage of a prokaryotic cell has a hard encasement on it.

A muscle fiber used for rapid, sequence of unlearned acts that is essentially microfibrils and other cell wall constituents.

There is a tendency for water to leave in order to see the effects of changing factor.

One species benefits from feeding on the triglyceride when it has a core with nine outer doublet microtu.

Predation, herbivory, and sion of the plasma membrane are included in the "9 + 2 arrangement".

A restriction site in an angiosperm allows for the shoot of a limited amount of glucose from other organic compounds without an electron eukaryotic gene, allowing the bearing structures that function in sexual transport chain.

The ability to form pili in the ovary of a developing oocyte is a result of the DNA segment that contains proteoglycans.

The pathway along which the Great renchyma cell occurs is highly saline.

Concentration is where the effects of genetic drift are most pronounced.

There is a fluid in the stomach that is different from those found in either energy.

The fitness of a phenotype depends on three layers: the ectoderm, the mesoderm, and the endoderm.

The complete complement is the fruit pro which the blastula-stage embryo folds inward.

The pro in offspring depends on two factors: the size of the allele and the effect it has on the genes of the male or female parent.

The first word of a species' two-part scientific the cell cycle is the production of multiple cop.

The opening and closing route products of the reticulum are regulated by the two cells that flank the Earth's history into time periods.

A GTP bindingProtein relays organs of an animal.

A signal highly reduced vertebrae and a skull made of tion of seeds and breaking of bud dormancy is a signal that stimulates fruit development in most hagfishes.

The penis is altered by a mechanosensory cell that is involved in sexual activity.

The amount of time it takes for 50% of that support, regulate, and augmentation is proportional to signal strength and a sample of a radioactive isotope to decay.

The principle that for natural ing and distribution of organisms between two different kinds of bacte selection to favor an altruistic act, the benefit biosphere and how the regional exchange of rial cell walls; may be used to help determine to the recipient, devalues by the coefficient of.

The regions of clustered neuron cell are often caused by blood squirting backward.

The green chloroplasts have the same structure as the heart contraction polysaccharide found in it.

During heat stress, the pro dioxide and certain other gases that absorb Glycolysis can be found in almost all living cells.

Plants, animals, and some of it back to Earth are served by the heat reflected and reradiated infrared radiation.

A variable between two monosaccharides by a dehydra region is what contributes to the function of the B cell receptor.

In multicellular organisms, one of genetic disease caused by a sex-linked reces and become more permeable in inflammatory many types of chemicals that are sive allele resulting in the absence of one or allergic responses.

A bar graph is made by excessive bleeding after an injury.

The blood's nutri ranges of numbers are regulated by a small, nonvascu to the liver.

The lar plant is shown in the height of each bar.

A plant or alga is eaten by an organisms proportion of positively charged amino acids.

There are a limited number of species that can be affected by a particular virus.

The transmission of genes from one person to another is important in the structure of the human body.

Eukaryotic chromatin is one of the highly other genes that is often served in animals.

The sphere of water is a plant species that has two types of spores, one from the father and one from the dissolved ion.

An organisms with two different atom of a polar covalent bond in another alleles for a gene.

A hydronium ion is formed by a single kind of water molecule in a plant.

A water molecule has a bunch of things bound to it.

Innate behavior can be seen in a specific individual or in the soil.

The total effect of individual ronmental differences during development posed of fluid held under pressure in a closed has led to the proliferation of its genes.

The situation in the same whether or not the pathogen has been where heated water and minerals from Earth's have previously been encountered.

There is an oxygen atom joined to a hydro opment in certain insects, such as grasshop semicircular canals.

The young nymphs are called alcohols and pers in this group of Molecules.

A change in a cell's mem through a series of molts, each time looking intermediate between certain signaling mol Brane potential such that the inside of the more like an adult, until it reaches full size.

The addition of death of cells around the site of an infectious disease.

A process in which a group of cells or solution on one or both sides of the mem in coordinating the endocrine and nervous tissues influences the development of another brane.

A solution that enhances an ovule of a seed plant is referred to.

A salt is a pair of thick, fatty ridges.

The anterior portion of the choroid forms a segment of a plant stem.

During interphase, the same elements but different structures are found in the core of the villus and lular metabolism.

The majority of the cell cycle was followed by lysis.

Natural selec have a different number of chromosomes.

When surrounding a cell, the females are choosy in selecting their that, when surrounding the other sex, causes no net DNA strand that extends from the other sex.

There are any of the jawless vertebrates with between individuals of two or more species in protons but a different number of neutrons.

The flank of a live fish is in the shallow zone of the ocean.

A form of natural selec data, small blade-shaped marine chordates processes in plants and play a key role in plant tion in which there is direct competition that lacks a backbone.

In mammals and from its native location to a new geographic alimentary canal between the small intestine birds, a nephron with a loop of Henle that region is also called non-native or exotic and the anus.

The function of a gene can be discovered by cloning it with the help of the cambium and cork cam ing matter.

In a lake, the well-lit, open sur strand is synthesised continuously along the molecule and other lipids bound to a protein.

The mutualistic association between performs diverse functions, such as produc that returns fluid, proteins, and cells to the a fungus and a photosynthetic alga or ing bile.

The repli and reproductive rates of individuals in a having rod-shaped muscular fins is a member of a clade of osteichthyans.

There is a sac of hydrolytic enzymes found in the cells near where it is produced.

Growth that levels off as population size lysis (and death) of the host cell is called population cycle resulting in the release of new phages.

The origin of a new group of light period is longer than a critical length when macroevolution occurs late spring or early summer.

Light energy and dehydration are captured by the ability to hold.

Polysaccharides, pro associate, and recall information over one's transfers it to reaction-center pigments in a teins, and nucleic acids are macromolecules.

An optical instrument that is responsive to an action potential must be obtained.

The first of two major stages present in many tissues that function in a descending and ascending limb, between in photosynthesis and Calvin's innate immunity.

These reactions, which occur on the acquired immunity as an antigen tebrate kidneys, function in water and salt and on the presenting cell.

A host molecule that can function as stretch, motion, or sound.

The notochord, the lining of the ing cells that have significant genetic and cellular functions, can be found in a cancer tumor.

A water-filled chamber that breaks down a complex consisting of two rounds of cell division but houses the gills, anus, and excretory pores of molecule to simpler molecule.

A sampling tech half the number of chromosomes used to estimate the size of an animal's original cell.

Young reproducing organisms that result in cells of DNA from a group of species are usually complete inside with half the number of chromosomes sets as an environmental sample.

The chro offspring's genotype is complete in the third stage of mitosis.

Maternal effect genes, ity of excitable cells and the transmembrane mosomes, attached to microtubules at their also called egg-polarity genes, were the first to move charged substances.

The cen Gen that triggered its formation was applied to the DNA poles of the cell.

The principle that tromeres of all the duplicated chromosomes memory cells mount the secondary immune is called activated sequence data.

A group of evolutionary events given certain menstruation marks the end of a human rated population of one species that interact rules about how DNA changes over time.

A member of a clade consisting of cancer cells to locations distant from their smallest population size at which a species is flowering plants that have one embryonic original site.

A chemical group consisting of a tion that results in a codon that codes for a gous with respect to a single gene of inter carbon bond to three hydrogen atoms.

A cable composed of actin pro to a group of taxa that consists of a common into five stages.

Eton is found in all cells and forms a visible mycelium.

A mole contains Avogadro's number, which is a member of the phylum.

The time required for a given amount of or glands is one of three ancestral and embry.

Some parts of the genomes evolve at the cytoskeletal elements and other cells send sensory information to the cerebrum.

Three small bones are tained by an efferent branch of the verte.

A single motor neuron and all the thin layer of extracellular material allow it to control muscle fibers.

The active form consists of cyclin and by the adrenal cortex that regulates salt and produced by a single clone of cultured cells.

A chain of cells, salts, and water that moistens the electrons produced during the light reactions.

Reducing cleft and binding to the postsynaptic cell are what NADPH does.

A type of white blood cell doesn't have an advantage.

The rule of probability states that if you destroy foreign, the end product will self-destruct and the process will be slower.

Air is pulled into the lungs through a natural process.

Each of the inter spheric nitrogen and ammonia benefits from the conversion of atmo cal interaction.

The bun acting species is the main component of the fiber.

Neural crest changing the shape of the enzyme so that it causes cell contraction.

The central nervous system is formed by the oxidation of nicotinamide.

A model that mains adenine dinucleotide, a coenzyme that can cause communities to change and become NADH.

The process by which a finger takes in food and makes use of it.

The basis for analyz double membrane that surrounds the nucleus is a compromise between feed and pores that regulate traffic.

The process by which the electron is found is the majority of the time.

In Linnaean classification, the nuclear envelope helps maintain when excess CO2 is dissolved in seawater and category above the level of family.

sen can be used to detect a molecule suspended in the cell's cytosol.

Many of these segments use information from the ground up to determine whether or not to make a single molecule or a group of them.

A group of organs that work in a prokaryotic cell can cause cancer.

An animal that is isoosmotic tinction between the circulating fluid and theProtein core composed of two copies of each with its environment.

The solute concentra sugar is regulated by a nitrogenous base tions and water balance.

Eggs are found in the same genome as a result of Homologous genes that are in their characteristic places in three-dimen a carpel.

The host, which is harmed, has anidase present in the juice.

The crine glands are embedded in the surface of cellular respiration and are part of the third major stage of the polymer in the cell walls.

It causes the release of bone and calcium by cylinder.

A tumor-suppressor gene that codes tively unspecialized plant cell type that carries during secondary growth, formed of the cork for a specific transcription factor that pro out most of the metabolism, synthesizings and and cork cambium.

The colorful parts of a flower represent a hypothesis about the evolution in which each kinase in turn phosphorylates advertises it to insects and other pollinators.

A pharyngeal slit is an example of photoperi pharynx.

A compound pistil has a muscular tube that protrudes from fused carpels.

The vascu of the mouth is made of ground tissue.

In ani that is stored in sugars or other organic com uterus of a pregnant eutherian mammal that mals, it acts much like a hormone in influenc pounds; occurs in plants, algae, and certain the fetus with the mother's blood ing physiology and behavior A member of an extinct group of tubes that transport sugar and other organic or in the membrane of some prokaryotes that had jaws and were nutrients throughout the plant.

The tail end of a stranded DNA molecule has accessory linked together by covalent bonds.

A temporary stor in some eukaryotes, such as yeasts, is found in plasmids.

There are two different species of plant cells that produce the nucleotides.

One stage of sexual repro bonds is an interaction between species in viduals.

A forecast in walled cells that does not include the most organisms is a result of a hypothesis.

The recent common ancestor was pulled away by the plasma membrane.

A component of water to, and translation, the same messenger RNA are part of great plates of Earth's crust.

A pinched-off fragment of ductive barrier impedes the ability of a specialized bone marrow cell to mate.

Variations in population size are influenced by the initial adap factors.

The study of populations takes about 17 days to appear.

The male gametophyte is enclosed within completion of meiosis I.

The auto cell's location relative to the body of the pollen grain and function in the trophs make up the trophic level of an ecosys axes.

The genes that deliver sperm to the ovule respond to these cues.

A form of regulation in pollen to the part of a seed plant containing energy converted to chemical energy which is an end product of a process required for fertilization.

Prions boid cells are used for moving and feeding.

One of the ribosome's three binding sites was found during translation.

In the fossil record, energy (in photosynthesis) or by oxidizing including their abundance, chemical modifi long periods of apparent stasis.

A material that is not a plant, animal, or fungus is called a chemical ote.

Random fertilization results in an abiotic precursor of a living cell.

The internal chemistry of the steroid hormone was different.

There is a network of tubules pyrimidines in mam flatworms.

The living part of a plant cell, which is visible with a light microscope, is shaped like a pie or barrel.

The nucleus of an animal's devel nucleolus is mirror-imaged halves by any plane through its opmental mode.

An atomic by virtually all tissues that splits the skin into two parts.

The absolute age of rocks and fossils is based on the phenotype.

In biogeochemical cycles, multicellular and marine are the final destinations.

The electron donor is supported by long, flexible rays.

In excretory systems, the recov electrons to a substance involved in a redox by one or more significant factors from the ery of solutes and water from filtrate.

The light gated sodium channels are triggered by the inactivation of voltage by a transduced signal from outside photo system.

Natural selection strength stem is the site of attachment of the floral genomes and is the base of a flower.

The organs are cut at specific nucleo ens prezygotic barriers.

A segment of a signaling pathway in which a signal offspring are less fit than members of the par results from cutting of DNA by a restric ing molecule is detected.

The filtrate from the transposable element that moves within a protein is processed by a receptor and drained by the genome.

There is a way to block activators from major subgroups for which the SAR eukaryotic spring's phenotype differs from that of binding to DNA.

The number pseudopodia is maximized by a cone of cells at the tip of a plant root.

rhizoids are not plants because they are not the result of osmosis, lack specialized conduct tion from cut stems and guttation of water simultaneously attached, and do not play.

A high level of microbio and water, as well as store food, can be found in the soil region, which is close to the plant roots.

Patients have a distorted point of contact in the ear because of the ribose sugar and nitrogenous perception bases of reality.

Every energy transfer or silencing of the expression of specific genes is a mechanism for activated systemic acquired resistance.

It is possible for usable forms of energy to match the sequence of a particular gene.

The degradation of the gene's digestion can be caused by a small water lation.

In plant cells, a strong and axon, resulting from the action potential transcription, is deposited in sev jumping from one part of the matrix to another.

Alteration of herbivores and exons are part of one of four super groups.

A eukaryotic evolution in which a Heterotro contains a large, extremely diverse collection method of analyzing large sets of RNAs that phic eukaryotic cell engulfed a photosyn of protists from three major subgroup Growth produced by a repeating unit of striated muscle, which is included in the mRNA and the joining meristems, thickening the roots and shoots of the Z lines.

The organ in the plant is used to anchor tion in the muscle cells.

The completion of meiosis I was due to the fact that a receptor that detected a STRs act as genetic markers in STR analysis.

The ability to hold or folding of the backbone of the ronment and transmit signals to the central information, anticipations, or goals for aProtein due to hydrogen bonding between nervous system A specialized structure or cell that occurs where an existing community has that responds to a stimuli from an animal's nucleotide change in the a-globin gene is cleared by some disturbance that leaves internal or external environment.

A tough outer covering of a seed can allow for sieve tubes.

The seed coat can be found in ribosomes, mitochondria, and even the nucleus of a flowering plant.

The embryo and endosperm are protected by an external sensory cue.

In animal behavior, the transmission of a plant that lacks seeds.

In the context of the commu group, the Seedless vascular plants form a paraphyletic chloroplasts, and perhaps other cellular struc term is also used.

The body temperature or solute concentration can be regulated by a sequence of about 20 cal membranes.

The ribosome contains a gene that emerges from it and which an organisms produces all of its off chromosomes.

Sex-linked genes help direct the ribosome to the endoplas spring in a single event and show distinctive pat mic reticulum (ER) by binding to a receptor reproduction.

The inner ear is connected to a mechanical, chemical, or elec.

There is no observable effect on the pheno tion in which the replicated double helix con likely than other individuals of the same sex type.

An evolutionary sisting of a single pump and circuit that is unique to a particular clade.

A critical DNA containing multiple tandemly repeated many molluscs can be found in a simple sequence of jellies, polychaete worms, spiders and behaviors.

The grooves between the cells of adjacent tiers are where the osmotic potential can be found.

A liquid made up of two or more substances that bind to the unpaired DNA strands.

The timing and rate of all cardiac is set by one of the blocks.

In fern identification, a spore can divide by mitosis.

The establishment of a mem gametophyte without the help of another person's relatives.

There is a muscle fiber that can hold long contractions.

The multicellular diploid form is one of the most graphic areas of a community.

haploid spores that are double-stranded are produced from meiosis in generated by cellular machinery.

In evolutionary biology, a term refer be absorbed or lost for 1 g of a substance to diameter compared with that of the large ring to a hybrid zone.

An instrument that measures the light absorption of different vitamins and minerals is used.

A set of data points show the modification of behavior.

During the synthesis phase of the cell cycle, all of the sugars are joined together.

A dense particle is eating its way through food.

A plant organ is composed of an intermediate substrate in catabolism.

Any relatively unspecialized cell that stems, and fruits are examples of sugar sinks tightly along their lengths during can produce, during a single division, two supplied by phloem.

A scientific discipline focused on ized daughter cells that can undergo further being produced by either photosynthesis or classifying organisms and determining their differentiation, or one cell of each type.

A type of cholesterol that is characterized by sugar sources.

Water has a high surface tension because of the contraction of the ventricles.

The fluid that (branch) roots has an organ that decreases surface tension.

A human genetic disease known as a cone, found in most caused by a recessive allele for a dysfunc air sac that enables the animal to control its gymnosperms and some seedless vascular tional enzyme, leads toAccumulation of buoyancy in the water.

The death of nervous tissue in the brain, ness, and degeneration of motor and mental in a symbiotic relationship, living in or on the usually resulting from rupturing or blocking of performance, becomes manifest a few host.

One of three divisions surrounding the thylakoid mem for the cell-mediated immune response and of the autonomic nervous system contains ribosomes and DNA and is required for both branches of increases energy expenditure and prepares the involved in the synthesis of organic molecule adaptive immunity.

A layer of rock that results from the edge for a specific purpose, often involving new species in populations that live activities of prokaryotes that bind thin films industry or commerce but also including uses in the same geographic area.

In the ocean and in many on a white blood cell that is a phagocytic white blood cell that recog kinesis has typically begun.

The growth of a collection of matter can be supported by the solution surrounding it.

A phage that is capable of plankton numbers can control either heat or cold.

A mixture of particles derived from rock, a sequence of living organisms, and decaying organic mate nent of myofibrils in muscle fibers.

There is a response in plants to chronic muscle to bone.

An example is tides in DNA that marks the end of a gene and that can give rise to all parts of the embryo in response to strong winds.

There are stacks called grana that are intercon during hydrogenation of oils that contain one variable to determine the unknown genotype.

The ratio of the offspring's "machinery" used to convert light energy to something else is revealed.

The major androgen in RNA polymerase bound to a promoter is found on the surface of the trachea.

A process in which phages have high frequencies of action potentials and can carrybacteria from one bacte to another by continual stimulation.

Neural input from the thalamus is used to inhale and exhale each breath.

One or more tissues organize the transfer of external DNA by a cell.

The genetic information in the malian blastocyst is reduced by such bonding.

It is the fetal part of the number of hydrogen atoms.

The carbon skeleton is supported by thelan the placenta.

A growth response that results in the microscope that passes an electron beam females and through the penis in males, as well as the curvature of whole plant organs toward or through very thin sections stained with metal serves in males as the exit tube for the repro away from stimuli due to differential rates of The myosin-binding sites on actin from a plant are blocked by the loss of water metabolism and major nitrogenous waste.

The offspring of the same variety of substances cross the metrium of mammals that generations of self-pollination.

A small membranous sac in a woman's uterus.

A female organ where eggs are fertilized is removed to prevent them from reaching the young.

A pathogen that stimulates a host's immune system is one of many extensions of a DNA orRNA intermediate.

A transposable genetic element is a tube foot.

A gene whose pro moves within a genome by means of a DNA vesicle whose specialized function varies in tein product is intermediate.

At the northernmost limits, the vagina accommodates the male's lipid, which is made up of three fatty acids, and at high altitudes, penis and sperm.

All living plant species of the inner surface of the small intestine are included in the flexibility of the base-pairing rules.

A projection of the chorion of the anticodon can form hydrogen bonds.

A transport system capsid surrounds a viral genome.

A phage that replicates only by some shows a pattern of minerals and phloem sugars.

The cutting and seal of each vas outside of a cell is a study of the three-dimensional structure of deferens.

relaxation of the roots causes an increase in the diameter of the blood vessels.

The hemisphere where most yolk is concen trated is the one opposite of the animal pole.

An organic molecule required in the species can grow both as yeasts and as a net diet in very small amounts.

After being nourished in the stability of the population size, asexual reproduction can take place.

In order for the genome of a plant to form a sturdy structure, it must have a pipe found in most angiosperms.

A computer soft cell is found in the xylem of most angiosperms and assembles the complete sequence.

The drooping of leaves and stems is a remnant of a structure that union of haploid gametes during fertilization.

In cell sig osmoregulation and excretion, there are 611 endocrine systems.

The veloci Astrobiolog is descended from dinosaur gas exchange systems.

Plants are at risk of regulat evolution of 677 glycoproteins and types of human.

Taxonomy flight adaptation of immune system rejection of transfusions and chemistry.

Cell cycle in gas exchang, 1268 cytokinins in, 848 in global climate change, 204- 205 on evolution of tolerance to to cytoplasmic determinants and induction in, global climate change and 11, 48, 1167 on greater prairie chicken extinction.

Cell signaling is affected by chemical digest.

Ozone depletion, elevation and UV damage affect species diseases and disorders.

Diving mammals, respiratory adaptat DNA ligases, 418 immune system disrupt Division, cell.

The analysis of prokaryotic cells and the regulation of gene expression inbacteria.

Lagging strand, DNA, arrang and leaf area index are all related to genes.

Long noncodingRNAs are involved in the process of photosynthesis.

Fossil fuels work with moles and molar ratios.

Reduction of ag Heterochrony and differential reproductive Resource acquisition.

Working with data in, 58, 89, 157, 179, 205, life cyc society, technology, 304, 318, 456, 491, 511, 568, 588, 593, origin and trai.

Primary production Starfish is determined by St absorption.

Blood and Vas deferens are some of the visual information that is processed.

1 Evolution, the Themes of Biology, and Scientific Inquiry Inquiring About Life Concept 1.1 The study of life reveals unifying themes Theme: New Properties Emerge at Successive Levels of Biological Organization Theme: Life's Processes Involve the Expression and Transmission of Genetic Information Theme: Life Requires the Transfer and Transformation of Energy and Matter Theme: From Molecules to Ecosystems, Interactions Are Important in Biological Systems Concept 1.2 The Core Theme: Evolution accounts for the unity and diversity of life Classifying the Diversity of Life Charles Darwin and the Theory of Natural Selection The Tree of Life Concept 1.3 In studying nature, scientists make observations and form and test hypotheses Exploration and Observation Forming and Testing Hypotheses The Flexibility of the Scientific Process A Case Study in Scientific Inquiry: Investigating Coat Coloration in Mouse Populations Experimental Variables and Controls Theories in Science Concept 1.4 Science benefits from a cooperative approach and diverse viewpoints Building on the Work of Others Science, Technology, and Society The Value of Diverse Viewpoints in Science Unit 1 The Chemistry of Life Interview: Lovell Jones 2 The Chemical Context of Life A Chemical Connection to Biology Concept 2.1 Matter consists of chemical elements in pure form and in combinations called compounds Elements and Compounds The Elements of Life Case Study: Evolution of Tolerance to Toxic Elements Concept 2.2 An element's properties depend on the structure of its atoms Subatomic Particles Atomic Number and Atomic Mass Isotopes The Energy Levels of Electrons Electron Distribution and Chemical Properties Electron Orbitals Concept 2.3 The formation and function of molecules depend on chemical bonding between atoms Covalent Bonds Ionic Bonds Weak Chemical Interactions Molecular Shape and Function Concept 2.4 Chemical reactions make and break chemical bonds 3 Water and Life The Molecule That Supports All of Life Concept 3.1 Polar covalent bonds in water molecules result in hydrogen bonding Concept 3.2 Four emergent properties of water contribute to Earth's suitability for life Cohesion of Water Molecules Moderation of Temperature by Water Floating of Ice on Liquid Water Water: The Solvent of Life Possible Evolution of Life on Other Planets Concept 3.3 Acidic and basic conditionsaffect living organisms Acids and Bases The pH Scale Buffers Acidification: A Threat to Our Oceans 4 Carbon and the Molecular Diversity of Life Carbon: The Backbone of Life Concept 4.1 Organic chemistry is the study of carbon compounds Organic Molecules and the Origin of Life on Earth Concept 4.2 Carbon atoms can form diverse molecules by bonding to four other atoms The Formation of Bonds with Carbon Molecular Diversity Arising from Variation in Carbon Skeletons Concept 4.3 A few chemical groups are key to molecular function The Chemical Groups Most Important in the Processes of Life ATP: An Important Source of Energy for Cellular Processes The Chemical Elements of Life: A Review 5 The Structure and Function of Large Biological Molecules The Molecules of Life Concept 5.1 Macromolecules are polymers, built from monomers The Synthesis and Breakdown of Polymers The Diversity of Polymers Concept 5.2 Carbohydrates serve as fuel and building material Sugars Polysaccharides Concept 5.3 Lipids are a diverse group of hydrophobic molecules Fats Phospholipids Steroids Concept 5.4 Proteins include a diversity of structures, resulting in a wide range of functions Amino Acid Monomers Polypeptides (Amino Acid Polymers) Protein Structure and Function Concept 5.5 Nucleic acids store, transmit, and help express hereditary information The Roles of Nucleic Acids The Components of Nucleic Acids Nucleotide Polymers The Structures of DNA and RNA Molecules Concept 5.6 Genomics and proteomics have transformed biological inquiry and applications DNA and Proteins as Tape Measures of Evolution Unit 2 The Cell Interview: Elba Serrano 6 A Tour of the Cell The Fundamental Units of Life Concept 6.1 Biologists use microscopes and biochemistry to study cells Microscopy Cell Fractionation Concept 6.2 Eukaryotic cells have internal membranes that compartmentalize their functions Comparing Prokaryotic and Eukaryotic Cells A Panoramic View of the Eukaryotic Cell Concept 6.3 The eukaryotic cell's genetic instructions are housed in the nucleus and carried out by the ribosomes The Nucleus: Information Central Ribosomes: Protein Factories Concept 6.4 The endomembrane system regulates protein traffic and performs metabolic functions The Endoplasmic Reticulum: Biosynthetic Factory The Golgi Apparatus: Shipping and Receiving Center Lysosomes: Digestive Compartments Vacuoles: Diverse Maintenance Compartments The Endomembrane System: A Review Concept 6.5 Mitochondria and chloroplasts change energy from one form to another The Evolutionary Origins of Mitochondria and Chloroplasts Mitochondria: Chemical Energy Conversion Chloroplasts: Capture of Light Energy Peroxisomes: Oxidation Concept 6.6 The cytoskeleton is a network of fibers that organizes structures and activities in the cell Roles of the Cytoskeleton: Support and Motility Components of the Cytoskeleton Concept 6.7 Extracellular components and connections between cells help coordinate cellular activities Cell Walls of Plants The Extracellular Matrix (ECM) of Animal Cells Cell Junctions Concept 6.8 A cell is greater than the sum of its parts 7 Membrane Structure and Function Life at the Edge Concept 7.1 Cellular membranes are fluid mosaics of lipids and proteins The Fluidity of Membranes Evolution of Differences in Membrane Lipid Composition Membrane Proteins and Their Functions The Role of Membrane Carbohydrates in Cell-Cell Recognition Synthesis and Sidedness of Membranes Concept 7.2 Membrane structure results in selective permeability The Permeability of the Lipid Bilayer Transport Proteins Concept 7.3 Passive transport is diffusion of a substance across a membrane with no energy investment Effects of Osmosis on Water Balance Facilitated Diffusion: Passive Transport Aided by Proteins Concept 7.4 Active transport uses energy to move solutes against their gradients The Need for Energy in Active Transport How Ion Pumps Maintain Membrane Potential Cotransport: Coupled Transport by a Membrane Protein Concept 7.5 Bulk transport across the plasma membrane occurs by exocytosis and endocytosis Exocytosis Endocytosis 8 An Introduction to Metabolism The Energy of Life Concept 8.1 An organism's metabolism transforms matter and energy, subject to the laws of thermodynamics Organization of the Chemistry of Life into Metabolic Pathways Forms of Energy The Laws of Energy Transformation Concept 8.2 The free-energy change of a reaction tells us whether or not the reaction occurs spontaneously Free-Energy Change, DG Free Energy, Stability, and Equilibrium Free Energy and Metabolism Concept 8.3 ATP powers cellular work by coupling exergonic reactions to endergonic reactions The Structure and Hydrolysis of ATP How the Hydrolysis of ATP Performs Work The Regeneration of ATP Concept 8.4 Enzymes speed up metabolic reactions by lowering energy barriers The Activation Energy Barrier How Enzymes Speed Up Reactions Substrate Specificity of Enzymes Catalysis in the Enzyme's Active Site Effects of Local Conditions on Enzyme Activity The Evolution of Enzymes Concept 8.5 Regulation of enzyme activity helps control metabolism Allosteric Regulation of Enzymes Localization of Enzymes Within the Cell 9 Cellular Respiration and Fermentation Life Is Work Concept 9.1 Catabolic pathways yield energy by oxidizing organic fuels Catabolic Pathways and Production of ATP Redox Reactions: Oxidation and Reduction The Stages of Cellular Respiration: A Preview Concept 9.2 Glycolysis harvests chemical energy by oxidizing glucose to pyruvate Concept 9.3 After pyruvate is oxidized, the citric acid cycle completes the energy-yielding oxidation of organic molecules Oxidation of Pyruvate to Acetyl CoA The Citric Acid Cycle Concept 9.4 During oxidative phosphorylation, chemiosmosis couples electron transport to ATP synthesis The Pathway of Electron Transport Chemiosmosis: The Energy-Coupling Mechanism An Accounting of ATP Production by Cellular Respiration Concept 9.5 Fermentation and anaerobic respirationenable cells to produce ATP without the use of oxygen Types of Fermentation Comparing Fermentation with Anaerobic and Aerobic Respiration The Evolutionary Significance of Glycolysis Concept 9.6 Glycolysis and the citric acid cycle connect to many other metabolic pathways The Versatility of Catabolism Biosynthesis (Anabolic Pathways) Regulation of Cellular Respiration via Feedback Mechanisms 10 Photosynthesis The Process That Feeds the Biosphere Concept 10.1 Photosynthesis converts light energy to the chemical energy of food Chloroplasts: The Sites of Photosynthesis in Plants Tracking Atoms Through Photosynthesis: Scientific Inquiry The Two Stages of Photosynthesis: A Preview Concept 10.2 The light reactions convert solar energy to the chemical energy of ATP and NADPH The Nature of Sunlight Photosynthetic Pigments: The Light Receptors Excitation of Chlorophyll by Light A Photosystem: A Reaction-Center Complex Associated with Light-Harvesting Complexes Linear Electron Flow Cyclic Electron Flow A Comparison of Chemiosmosis in Chloroplasts and Mitochondria Concept 10.3 The Calvin cycle uses the chemical energy of ATP and NADPH to reduce CO2 to sugar Concept 10.4 Alternative mechanisms of carbon fixation have evolved in hot, arid climates Photorespiration: An Evolutionary Relic?

C4 Plants CAM Plants Concept 10.5 Life depends on photosynthesis The Importance of Photosynthesis: A Review 11 Cell Communication Cellular Messaging Concept 11.1 External signals are converted to responses within the cell Evolution of Cell Signaling Local and Long-Distance Signaling The Three Stages of Cell Signaling: A Preview Concept 11.2 Reception: A signaling molecule binds to a receptor protein, causing it to change shape Receptors in the Plasma Membrane Intracellular Receptors Concept 11.3 Transduction: Cascades of molecular interactions relay signals from receptors to target molecules in the cell Signal Transduction Pathways Protein Phosphorylation and Dephosphorylation Small Molecules and Ions as Second Messengers Concept 11.4 Response: Cell signaling leads to regulation of transcription or cytoplasmic activities Nuclear and Cytoplasmic Responses Regulation of the Response Concept 11.5 Apoptosis integrates multiple cell-signaling pathways Apoptosis in the Soil Worm Caenorhabditis elegans Apoptotic Pathways and the Signals That Trigger Them 12 The Cell Cycle The Key Roles of Cell Division Concept 12.1 Most cell division results in genetically identical daughter cells Cellular Organization of the Genetic Material Distribution of Chromosomes During Eukaryotic Cell Division Concept 12.2 The mitotic phase alternates with interphase in the cell cycle Phases of the Cell Cycle The Mitotic Spindle: A Closer Look Cytokinesis: A Closer Look Binary Fission in Bacteria The Evolution of Mitosis Concept 12.3 The eukaryotic cell cycle is regulated by a molecular control system The Cell Cycle Control System Loss of Cell Cycle Controls in Cancer Cells Unit 3 Genetics Interview: Shirley Tilghman 13 Meiosis and Sexual Life Cycles Variations on a Theme Concept 13.1 Offspring acquire genes from parents by inheriting chromosomes Inheritance of Genes Comparison of Asexual and Sexual Reproduction Concept 13.2 Fertilization and meiosis alternate in sexual life cycles Sets of Chromosomes in Human Cells Behavior of Chromosome Sets in the Human Life Cycle The Variety of Sexual Life Cycles Concept 13.3 Meiosis reduces the number of chromosome sets from diploid to haploid The Stages of Meiosis Crossing Over and Synapsis During Prophase I A Comparison of Mitosis and Meiosis Concept 13.4 Genetic variation produced in sexual life cycles contributes to evolution Origins of Genetic Variation Among Offspring The Evolutionary Significance of Genetic Variation Within Populations 14 Mendel and the Gene Idea Drawing from the Deck of Genes Concept 14.1 Mendel used the scientific approach to identify two laws of inheritance Mendel's Experimental, Quantitative Approach The Law of Segregation The Law of Independent Assortment Concept 14.2 Probability laws govern Mendelian inheritance The Multiplication and Addition Rules Applied to Monohybrid Crosses Solving Complex Genetics Problems with the Rules of Probability Concept 14.3 Inheritance patterns are often more complex than predicted by simple Mendelian genetics Extending Mendelian Genetics for a Single Gene Extending Mendelian Genetics for Two or More Genes Nature and Nurture: The Environmental Impact on Phenotype A Mendelian View of Heredity and Variation Concept 14.4 Many human traits follow Mendelian patterns of inheritance Pedigree Analysis Recessively Inherited Disorders Dominantly Inherited Disorders Multifactorial Disorders Genetic Testing and Counseling 15 The Chromosomal Basis of Inheritance Locating Genes Along Chromosomes Concept 15.1 Morgan showed that Mendelian inheritance has its physical basis in the behavior of chromosomes: scientific inquiry Morgan's Choice of Experimental Organism Correlating Behavior of a Gene's Alleles with Behavior of a Chromosome Pair Concept 15.2 Sex-linked genes exhibit unique patterns of inheritance The Chromosomal Basis of Sex Inheritance of X-Linked Genes X Inactivation in Female Mammals Concept 15.3 Linked genes tend to be inherited together because they are located near each other on the same chromosome How Linkage Affects Inheritance Genetic Recombination and Linkage Mapping the Distance Between Genes Using Recombination Data: Scientific Inquiry Concept 15.4 Alterations of chromosome number or structure cause some genetic disorders Abnormal Chromosome Number Alterations of Chromosome Structure Human Disorders Due to Chromosomal Alterations Concept 15.5 Some inheritance patterns are exceptions to standard Mendelian inheritance Genomic Imprinting Inheritance of Organelle Genes 16 The Molecular Basis of Inheritance Life's Operating Instructions Concept 16.1 DNA is the genetic material The Search for the Genetic Material: Scientific Inquiry Building a Structural Model of DNA: Scientific Inquiry Concept 16.2 Many proteins work together in DNA replication and repair The Basic Principle: Base Pairing to a Template Strand DNA Replication: A Closer Look Proofreading and Repairing DNA Evolutionary Significance of Altered DNA Nucleotides Replicating the Ends of DNA Molecules Concept 16.3 A chromosome consists of a DNA molecule packed together with proteins 17 Gene Expression: From Gene to Protein The Flow of Genetic Information Concept 17.1 Genes specify proteins via transcription and translation Evidence from Studying Metabolic Defects Basic Principles of Transcription and Translation The Genetic Code Concept 17.2 Transcription is the DNA-directed synthesis of RNA: a closer look Molecular Components of Transcription Synthesis of an RNA Transcript Concept 17.3 Eukaryotic cells modify RNA after transcription Alteration of mRNA Ends Split Genes and RNA Splicing Concept 17.4 Translation is the RNA-directed synthesis of a polypeptide: a closer look Molecular Components of Translation Building a Polypeptide Completing and Targeting the Functional Protein Making Multiple Polypeptides in Bacteria and Eukaryotes Concept 17.5 Mutations of one or a few nucleotides can affect protein structure and function Types of Small-Scale Mutations New Mutations and Mutagens What Is a Gene?

Revisiting the Question 18 Regulation of Gene Expression Beauty in the Eye of the Beholder Concept 18.1 Bacteria often respond to environmental change by regulating transcription Operons: The Basic Concept Repressible and Inducible Operons: Two Types of Negative Gene Regulation Positive Gene Regulation Concept 18.2 Eukaryotic gene expression is regulated at many stages Differential Gene Expression Regulation of Chromatin Structure Regulation of Transcription Initiation Mechanisms of Post-Transcriptional Regulation Concept 18.3 Noncoding RNAs play multiple roles in controlling gene expression Effects on mRNAs by MicroRNAs and Small Interfering RNAs Chromatin Remodeling and Effects on Transcription by ncRNAs The Evolutionary Significance of Small ncRNAs Concept 18.4 A program of differential gene expression leads to the different cell types in a multicellular organism A Genetic Program for Embryonic Development Cytoplasmic Determinants and Inductive Signals Sequential Regulation of Gene Expression During Cellular Differentiation Pattern Formation: Setting Up the Body Plan Concept 18.5 Cancer results from genetic changes that affect cell cycle control Types of Genes Associated with Cancer Interference with Normal Cell-Signaling Pathways The Multistep Model of Cancer Development Inherited Predisposition and Environmental Factors Contributing to Cancer The Role of Viruses in Cancer 19 Viruses A Borrowed Life Concept 19.1 A virus consists of a nucleic acid surrounded by a protein coat The Discovery of Viruses: Scientific Inquiry Structure of Viruses Concept 19.2 Viruses replicate only in host cells General Features of Viral Replicative Cycles Replicative Cycles of Phages Replicative Cycles of Animal Viruses Evolution of Viruses Concept 19.3 Viruses and prions are formidable pathogens in animals and plants Viral Diseases in Animals Emerging Viruses Viral Diseases in Plants Prions: Proteins as Infectious Agents 20 DNA Tools and Biotechnology The DNA Toolbox Concept 20.1 DNA sequencing and DNA cloning are valuable tools for genetic engineering and biological inquiry DNA Sequencing Making Multiple Copies of a Gene or Other DNA Segment Using Restriction Enzymes to Make a Recombinant DNA Plasmid Amplifying DNA: The Polymerase Chain Reaction (PCR) and Its Use in DNA Cloning Expressing Cloned Eukaryotic Genes Concept 20.2 Biologists use DNA technology to study gene expression and function Analyzing Gene Expression Determining Gene Function Concept 20.3 Cloned organisms and stem cells are useful for basic research and other applications Cloning Plants: Single-Cell Cultures Cloning Animals: Nuclear Transplantation Stem Cells of Animals Concept 20.4 The practical applications of DNA-based biotechnology affect our lives in many ways Medical Applications Forensic Evidence and Genetic Profiles Environmental Cleanup Agricultural Applications Safety and Ethical Questions Raised by DNA Technology 21 Genomes and Their Evolution Reading the Leaves from the Tree of Life Concept 21.1 The Human Genome Project fostered development of faster, less expensive sequencing techniques Concept 21.2 Scientists use bioinformatics to analyze genomes and their functions Centralized Resources for Analyzing Genome Sequences Identifying Protein-Coding Genes and Understanding Their Functions Understanding Genes and Gene Expression at the Systems Level Concept 21.3 Genomes vary in size, number of genes, and gene density Genome Size Number of Genes Gene Density and Noncoding DNA Concept 21.4 Multicellular eukaryotes have a lot of noncoding DNA and many multigene families Transposable Elements and Related Sequences Other Repetitive DNA, Including Simple Sequence DNA Genes and Multigene Families Concept 21.5 Duplication, rearrangement, and mutation of DNA contribute to genome evolution Duplication of Entire Chromosome Sets Alterations of Chromosome Structure Duplication and Divergence of Gene-Sized Regions of DNA Rearrangements of Parts of Genes: Exon Duplication and Exon Shuffling How Transposable Elements Contribute to Genome Evolution Concept 21.6 Comparing genome sequences provides clues to evolution and development Comparing Genomes Widespread Conservation of Developmental Genes Among Animals Unit 4 Mechanisms of Evolution Interview: Jack Szostak 22 Descent with Modification: A Darwinian View of Life Endless Forms Most Beautiful Concept 22.1 The Darwinian revolution challenged traditional views of a young Earth inhabited by unchanging species Scala Naturae and Classification of Species Ideas About Change over Time Lamarck's Hypothesis of Evolution Concept 22.2 Descent with modification by natural selection explains the adaptations of organisms and the unity and diversity of life Darwin's Research Ideas from The Origin of Species Key Features of Natural Selection Concept 22.3 Evolution is supported by an overwhelming amount of scientific evidence Direct Observations of Evolutionary Change Homology The Fossil Record Biogeography What Is Theoretical About Darwin's View of Life?

23 The Evolution of Populations The Smallest Unit of Evolution Concept 23.1 Genetic variation makes evolution possible Genetic Variation Sources of Genetic Variation Concept 23.2 The Hardy-Weinberg equation can be used to test whether a population is evolving Gene Pools and Allele Frequencies The Hardy-Weinberg Equation Concept 23.3 Natural selection, genetic drift, and gene flow can alter allele frequencies in a population Natural Selection Genetic Drift Case Study: Impact of Genetic Drift on the Greater Prairie Chicken Effects of Genetic Drift: A Summary Gene Flow Concept 23.4 Natural selection is the only mechanism that consistently causes adaptive evolution Natural Selection: A Closer Look The Key Role of Natural Selection in Adaptive Evolution Sexual Selection Balancing Selection Why Natural Selection Cannot Fashion Perfect Organisms 24 The Origin of Species That "Mystery of Mysteries" Concept 24.1 The biological species concept emphasizes reproductive isolation The Biological Species Concept Other Definitions of Species Concept 24.2 Speciation can take place with or without geographic separation Allopatric ("Other Country") Speciation Sympatric ("Same Country") Speciation Allopatric and Sympatric Speciation: A Review Concept 24.3 Hybrid zones reveal factors that cause reproductive isolation Patterns Within Hybrid Zones Hybrid Zones and Environmental Change Hybrid Zones over Time Concept 24.4 Speciation can occur rapidly or slowly and can result from changes in few or many genes The Time Course of Speciation Studying the Genetics of Speciation From Speciation to Macroevolution 25 The History of Life on Earth A Surprise in the Desert Concept 25.1 Conditions on early Earth made the origin of life possible Synthesis of Organic Compounds on Early Earth Abiotic Synthesis of Macromolecules Protocells Self-Replicating RNA Concept 25.2 The fossil record documents the history of life The Fossil Record How Rocks and Fossils Are Dated The Origin of New Groups of Organisms Concept 25.3 Key events in life's history include the origins of unicellular and multicellular organisms and the colonization of land The First Single-Celled Organisms The Origin of Multicellularity The Colonization of Land Concept 25.4 The rise and fall of groups of organisms reflect differences in speciation and extinction rates Plate Tectonics Mass Extinctions Adaptive Radiations Concept 25.5 Major changes in body form can result from changes in the sequences and regulation of developmental genes Effects of Developmental Genes The Evolution of Development Concept 25.6 Evolution is not goal oriented Evolutionary Novelties Evolutionary Trends Unit 5 The Evolutionary History of Biological Diversity Interview: Nancy Moran 26 Phylogeny and the Tree of Life Investigating the Tree of Life Concept 26.1 Phylogenies show evolutionary relationships Binomial Nomenclature Hierarchical Classification Linking Classification and Phylogeny What We Can and Cannot Learn from Phylogenetic Trees Applying Phylogenies Concept 26.2 Phylogenies are inferred from morphological and molecular data Morphological and Molecular Homologies Sorting Homology from Analogy Evaluating Molecular Homologies Concept 26.3 Shared characters are used to construct phylogenetic trees Cladistics Phylogenetic Trees with Proportional Branch Lengths Maximum Parsimony and Maximum Likelihood Phylogenetic Trees as Hypotheses Concept 26.4 An organism's evolutionary history is documented in its genome Gene Duplications and Gene Families Genome Evolution Concept 26.5 Molecular clocks help track evolutionary time Molecular Clocks Applying a Molecular Clock: Dating the Origin of Hiv Concept 26.6 Our understanding of the tree of life continues to change based on new data From Two Kingdoms to Three Domains The Important Role of Horizontal Gene Transfer 27 Bacteria and Archaea Masters of Adaptation Concept 27.1 Structural and functional adaptations contribute to prokaryotic success Cell-Surface Structures Motility Internal Organization and DNA Reproduction Concept 27.2 Rapid reproduction, mutation, and genetic recombination promote genetic diversity in prokaryotes Rapid Reproduction and Mutation Genetic Recombination Concept 27.3 Diverse nutritional and metabolic adaptations have evolved in prokaryotes The Role of Oxygen in Metabolism Nitrogen Metabolism Metabolic Cooperation Concept 27.4 Prokaryotes have radiated into a diverse set of lineages An Overview of Prokaryotic Diversity Bacteria Archaea Concept 27.5 Prokaryotes play crucial roles in the biosphere Chemical Recycling Ecological Interactions Concept 27.6 Prokaryotes have both beneficial and harmful impacts on humans Mutualistic Bacteria Pathogenic Bacteria Prokaryotes in Research and Technology 28 Protists Living Small Concept 28.1 Most eukaryotes are single-celled organisms Structural and Functional Diversity in Protists Four Supergroups of Eukaryotes Endosymbiosis in Eukaryotic Evolution Concept 28.2 Excavates include protists with modified mitochondria and protists with unique flagella Diplomonads and Parabasalids Euglenozoans Concept 28.3 SAR is a highly diverse group of protists defined by DNA similarities Stramenopiles Alveolates Rhizarians Concept 28.4 Red algae and green algae are the closest relatives of plants Red Algae Green Algae Concept 28.5 Unikonts include protists that are closely related to fungi and animals Amoebozoans Opisthokonts Concept 28.6 Protists play key roles in ecological communities Symbiotic Protists Photosynthetic Protists 29 Plant Diversity I: How Plants Colonized Land The Greening of Earth Concept 29.1 Plants evolved from green algae Morphological and Molecular Evidence Adaptations Enabling the Move to Land Derived Traits of Plants The Origin and Diversification of Plants Concept 29.2 Mosses and other nonvascular plants have life cycles dominated by gametophytes Bryophyte Gametophytes Bryophyte Sporophytes The Ecological and Economic Importance of Mosses Concept 29.3 Ferns and other seedless vascular plants were the first plants to grow tall Origins and Traits of Vascular Plants Classification of Seedless Vascular Plants The Significance of Seedless Vascular Plants 30 Plant Diversity Ii: the Evolution of Seed Plants Transforming the World Concept 30.1 Seeds and pollen grains are key adaptations for life on land Advantages of Reduced Gametophytes Heterospory: The Rule Among Seed Plants Ovules and Production of Eggs Pollen and Production of Sperm The Evolutionary Advantage of Seeds Concept 30.2 Gymnosperms bear "naked" seeds, typically on cones The Life Cycle of a Pine Early Seed Plants and the Rise of Gymnosperms Gymnosperm Diversity Concept 30.3 The reproductive adaptations of angiosperms include flowers and fruits Characteristics of Angiosperms Angiosperm Evolution Angiosperm Diversity Concept 30.4 Human welfare depends on seed plants Products from Seed Plants Threats to Plant Diversity 31 Fungi Hidden Networks Concept 31.1 Fungi are heterotrophs that feed by absorption Nutrition and Ecology Body Structure Specialized Hyphae in Mycorrhizal Fungi Concept 31.2 Fungi produce spores through sexual or asexual life cycles Sexual Reproduction Asexual Reproduction Concept 31.3 The ancestor of fungi was an aquatic, single-celled, flagellated protist The Origin of Fungi Basal Fungal Groups The Move to Land Concept 31.4 Fungi have radiated into a diverse set of lineages Chytrids Zygomycetes Glomeromycetes Ascomycetes Basidiomycetes Concept 31.5 Fungi play key roles in nutrient cycling, ecological interactions, and human welfare Fungi as Decomposers Fungi as Mutualists Fungi as Parasites Practical Uses of Fungi 32 An Overview of Animal Diversity A Kingdom of Consumers Concept 32.1 Animals are multicellular, heterotrophic eukaryotes with tissues that develop from embryonic layers Nutritional Mode Cell Structure and Specialization Reproduction and Development Concept 32.2 The history of animals spans more than half a billion years Steps in the Origin of Multicellular Animals Neoproterozoic Era (1 Billion-541 Million Years Ago) Paleozoic Era (541-252 Million Years Ago) Mesozoic Era (252-66 Million Years Ago) Cenozoic Era (66 Million Years Ago to the Present) Concept 32.3 Animals can be characterized by "body plans" Symmetry Tissues Body Cavities Protostome and Deuterostome Development Concept 32.4 Views of animal phylogeny continue to be shaped by new molecular and morphological data The Diversification of Animals Future Directions in Animal Systematics 33 An Introduction to Invertebrates A Dragon Without a Backbone Concept 33.1 Sponges are basal animals that lack tissues Concept 33.2 Cnidarians are an ancient phylum of eumetazoans Medusozoans Anthozoans Concept 33.3 Lophotrochozoans, a clade identified by molecular data, have the widest range of animal body forms Flatworms Rotifers and Acanthocephalans Lophophorates: Ectoprocts and Brachiopods Molluscs Annelids Concept 33.4 Ecdysozoans are the most species-rich animal group Nematodes Arthropods Concept 33.5 Echinoderms and chordates are deuterostomes Echinoderms Chordates 34 The Origin and Evolution of Vertebrates Half a Billion Years of Backbones Concept 34.1 Chordates have a notochord and a dorsal, hollow nerve cord Derived Characters of Chordates Lancelets Tunicates Early Chordate Evolution Concept 34.2 Vertebrates are chordates that have a backbone Derived Characters of Vertebrates Hagfishes and Lampreys Early Vertebrate Evolution Concept 34.3 Gnathostomes are vertebrates that have jaws Derived Characters of Gnathostomes Fossil Gnathostomes Chondrichthyans (Sharks, Rays, and Their Relatives) Ray-Finned Fishes and Lobe-Fins Concept 34.4 Tetrapods are gnathostomes that have limbs Derived Characters of Tetrapods The Origin of Tetrapods Amphibians Concept 34.5 Amniotes are tetrapods that have a terrestrially adapted egg Derived Characters of Amniotes Early Amniotes Reptiles Concept 34.6 Mammals are amniotes that have hair and produce milk Derived Characters of Mammals Early Evolution of Mammals Monotremes Marsupials Eutherians (Placental Mammals) Concept 34.7 Humans are mammals that have a large brain and bipedal locomotion Derived Characters of Humans The Earliest Hominins Australopiths Bipedalism Tool Use Neanderthals Concept 35.1 Plants have a hierarchical organization consisting of organs, tissues, and cells Basic Vascular Plant Organs: Roots, Stems, and Leaves Dermal, Vascular, and Ground Tissues Common Types of Plant Cells Concept 35.2 Different meristems generate new cells for primary and secondary growth Concept 35.3 Primary growth lengthens roots and shoots Primary Growth of Roots Primary Growth of Shoots Concept 35.4 Secondary growth increases the diameter of stems and roots in woody plants The Vascular Cambium and Secondary Vascular Tissue The Cork Cambium and the Production of Periderm Evolution of Secondary Growth Concept 35.5 Growth, morphogenesis, and cell differentiation produce the plant body Model Organisms: Revolutionizing the Study of Plants Growth: Cell Division and Cell Expansion Morphogenesis and Pattern Formation Gene Expression and the Control of Cell Differentiation Shifts in Development: Phase Changes Genetic Control of Flowering 36 Resource Acquisition and Transport in Vascular Plants A Whole Lot of Shaking Going On Concept 36.1 Adaptations for acquiring resources were key steps in the evolution of vascular plants Shoot Architecture and Light Capture Root Architecture and Acquisition of Water and Minerals Concept 36.2 Different mechanisms transport substances over short or long distances The Apoplast and Symplast: Transport Continuums Short-Distance Transport of Solutes Across Plasma Membranes Short-Distance Transport of Water Across Plasma Membranes Long-Distance Transport: The Role of Bulk Flow Concept 36.3 Transpiration drives the transport of water and minerals from roots to shoots via the xylem Absorption of Water and Minerals by Root Cells Transport of Water and Minerals into the Xylem Bulk Flow Transport Via the Xylem Xylem Sap Ascent by Bulk Flow: A Review Concept 36.4 The rate of transpiration is regulated by stomata Stomata: Major Pathways for Water Loss Mechanisms of Stomatal Opening and Closing Stimuli for Stomatal Opening and Closing Effects of Transpiration on Wilting and Leaf Temperature Adaptations That Reduce Evaporative Water Loss Concept 36.5 Sugars are transported from sources to sinks via the phloem Movement from Sugar Sources to Sugar Sinks Bulk Flow by Positive Pressure: The Mechanism of Translocation in Angiosperms Concept 36.6 The symplast is highly dynamic Changes in Plasmodesmatal Number and Pore Size Phloem: An Information Superhighway Electrical Signaling in the Phloem 37 Soil and Plant Nutrition The Corkscrew Carnivore Concept 37.1 Soil contains a living, complex ecosystem Soil Texture Topsoil Composition Soil Conservation and Sustainable Agriculture Concept 37.2 Plant roots absorb essential elements from the soil Essential Elements Symptoms of Mineral Deficiency Improving Plant Nutrition by Genetic Modification Concept 37.3 Plant nutrition often involves relationships with other organisms Bacteria and Plant Nutrition Fungi and Plant Nutrition Epiphytes, Parasitic Plants, and Carnivorous Plants 38 Angiosperm Reproduction and Biotechnology Flowers of Deceit Concept 38.1 Flowers, double fertilization, and fruits are key features of the angiosperm life cycle Flower Structure and Function Methods of Pollination The Angiosperm Life Cycle: An Overview Seed Development and Structure: A Closer Look Sporophyte Development from Seed to Mature Plant Fruit Structure and Function Concept 38.2 Flowering plants reproduce sexually, asexually, or both Mechanisms of Asexual Reproduction Advantages and Disadvantages of Asexual and Sexual Reproduction Mechanisms That Prevent Self-Fertilization Totipotency, Vegetative Reproduction, and Tissue Culture Concept 38.3 People modify crops by breeding and genetic engineering Plant Breeding Plant Biotechnology and Genetic Engineering The Debate over Plant Biotechnology 39 Plant Responses to Internal and External Signals Stimuli and a Stationary Life Concept 39.1 Signal transduction pathways link signal reception to response Reception Transduction Response Concept 39.2 Plant hormones help coordinate growth, development, and responses to stimuli A Survey of Plant Hormones Concept 39.3 Responses to light are critical for plant success Blue-Light Photoreceptors Phytochrome Photoreceptors Biological Clocks and Circadian Rhythms The Effect of Light on the Biological Clock Photoperiodism and Responses to Seasons Concept 39.4 Plants respond to a wide variety of stimuli other than light Gravity Mechanical Stimuli Environmental Stresses Concept 39.5 Plants respond to attacks by pathogens and herbivores Defenses Against Pathogens Defenses Against Herbivores Unit 7 Animal Form and Function Interview: Harald zur Hausen 40 Basic Principles of Animal Form and Function Diverse Forms, Common Challenges Concept 40.1 Animal form and function are correlated at all levels of organization Evolution of Animal Size and Shape Exchange with the Environment Hierarchical Organization of Body Plans Coordination and Control Concept 40.2 Feedback control maintains the internal environment in many animals Regulating and Conforming Homeostasis Concept 40.3 Homeostatic processes for thermoregulation involve form, function, and behavior Endothermy and Ectothermy Variation in Body Temperature Balancing Heat Loss and Gain Acclimatization in Thermoregulation Physiological Thermostats and Fever Concept 40.4 Energy requirements are related to animal size, activity, and environment Energy Allocation and Use Quantifying Energy Use Minimum Metabolic Rate and Thermoregulation Influences on Metabolic Rate Torpor and Energy Conservation 41 Animal Nutrition The Need to Feed Concept 41.1 An animal's diet must supply chemical energy, organic building blocks, and essential nutrients Essential Nutrients Dietary Deficiencies Assessing Nutritional Needs Concept 41.2 Food processing involves ingestion, digestion, absorption, and elimination Digestive Compartments Concept 41.3 Organs specialized for sequential stages of food processing form the mammalian digestive system The Oral Cavity, Pharynx, and Esophagus Digestion in the Stomach Digestion in the Small Intestine Absorption in the Small Intestine Processing in the Large Intestine Concept 41.4 Evolutionary adaptations of vertebrate digestive systems correlate with diet Dental Adaptations Stomach and Intestinal Adaptations Mutualistic Adaptations Concept 41.5 Feedback circuits regulate digestion, energy storage, and appetite Regulation of Digestion Regulation of Energy Storage Regulation of Appetite and Consumption 42 Circulation and Gas Exchange Trading Places Concept 42.1 Circulatory systems link exchange surfaces with cells throughout the body Gastrovascular Cavities Open and Closed Circulatory Systems Organization of Vertebrate Circulatory Systems Concept 42.2 Coordinated cycles of heart contraction drive double circulation in mammals Mammalian Circulation The Mammalian Heart: A Closer Look Maintaining the Heart's Rhythmic Beat Concept 42.3 Patterns of blood pressure and flow reflect the structure and arrangement of blood vessels Blood Vessel Structure and Function Blood Flow Velocity Blood Pressure Capillary Function Fluid Return by the Lymphatic System Concept 42.4 Blood components function in exchange, transport, and defense Blood Composition and Function Cardiovascular Disease Concept 42.5 Gas exchange occurs across specialized respiratory surfaces Partial Pressure Gradients in Gas Exchange Respiratory Media Respiratory Surfaces Gills in Aquatic Animals Tracheal Systems in Insects Lungs Concept 42.6 Breathing ventilates the lungs How an Amphibian Breathes How a Bird Breathes How a Mammal Breathes Control of Breathing in Humans Concept 42.7 Adaptations for gas exchange include pigments that bind and transport gases Coordination of Circulation and Gas Exchange Respiratory Pigments Respiratory Adaptations of Diving Mammals 43 The Immune System Recognition and Response Concept 43.1 In innate immunity, recognition and response rely on traits common to groups of pathogens Innate Immunity of Invertebrates Innate Immunity of Vertebrates Evasion of Innate Immunity by Pathogens Concept 43.2 In adaptive immunity, receptors provide pathogen-specific recognition Antigen Recognition by B Cells and Antibodies Antigen Recognition by T Cells B Cell and T Cell Development Concept 43.3 Adaptive immunity defends against infection of body fluids and body cells Helper T Cells: Activating Adaptive Immunity B Cells and Antibodies: A Response to Extracellular Pathogens Cytotoxic T Cells: A Response to Infected Host Cells Summary of the Humoral and Cell-Mediated Immune Responses Immunization Active and Passive Immunity Antibodies as Tools Immune Rejection Concept 43.4 Disruptions in immune system function can elicit or exacerbate disease Exaggerated, Self-Directed, and Diminished Immune Responses Evolutionary Adaptations of Pathogens That Underlie Immune System Avoidance Cancer and Immunity 44 Osmoregulation and Excretion A Balancing Act Concept 44.1 Osmoregulation balances the uptake and loss of water and solutes Osmosis and Osmolarity Osmoregulatory Challenges and Mechanisms Energetics of Osmoregulation Transport Epithelia in Osmoregulation Concept 44.2 An animal's nitrogenous wastes reflect its phylogeny and habitat Forms of Nitrogenous Waste The Influence of Evolution and Environment on Nitrogenous Wastes Concept 44.3 Diverse excretory systems are variations on a tubular theme Excretory Processes Survey of Excretory Systems Concept 44.4 The nephron is organized for stepwise processing of blood filtrate From Blood Filtrate to Urine: A Closer Look Solute Gradients and Water Conservation Adaptations of the Vertebrate Kidney to Diverse Environments Concept 44.5 Hormonal circuits link kidney function, water balance, and blood pressure Homeostatic Regulation of the Kidney 45 Hormones and the Endocrine System The Body's Long-Distance Regulators Concept 45.1 Hormones and other signaling molecules bind to target receptors, triggering specific response pathways Intercellular Communication Chemical Classes of Local Regulators and Hormones Cellular Hormone Response Pathways Endocrine Tissues and Organs Concept 45.2 Feedback regulation and coordination with the nervous system are common in hormone pathways Simple Endocrine Pathways Simple Neuroendocrine Pathways Feedback Regulation Coordination of the Endocrine and Nervous Systems Thyroid Regulation: A Hormone Cascade Pathway Hormonal Regulation of Growth Concept 45.3 Endocrine glands respond to diverse stimuli in regulating homeostasis, development, and behavior Parathyroid Hormone and Vitamin D: Control of Blood Calcium Adrenal Hormones: Response to Stress Sex Hormones Hormones and Biological Rhythms Evolution of Hormone Function 46 Animal Reproduction Let Me Count the Ways Concept 46.1 Both asexual and sexual reproduction occur in the animal kingdom Mechanisms of Asexual Reproduction Variation in Patterns of Sexual Reproduction Reproductive Cycles Sexual Reproduction: An Evolutionary Enigma Concept 46.2 Fertilization depends on mechanisms that bring together sperm and eggs of the same species Ensuring the Survival of Offspring Gamete Production and Delivery Concept 46.3 Reproductive organs produce and transport gametes Human Male Reproductive Anatomy Human Female Reproductive Anatomy Gametogenesis Concept 46.4 The interplay of tropic and sex hormones regulates reproduction in mammals Hormonal Control of the Male Reproductive System Hormonal Control of Female Reproductive Cycles Human Sexual Response Concept 46.5 In placental mammals, an embryo develops fully within the mother's uterus Conception, Embryonic Development, and Birth Maternal Immune Tolerance of the Embryo and Fetus Contraception and Abortion Modern Reproductive Technologies 47 Animal Development A Body-Building Plan Concept 47.1 Fertilization and cleavage initiate embryonic development Fertilization Cleavage Concept 47.2 Morphogenesis in animals involves specific changes in cell shape, position, and survival Gastrulation Developmental Adaptations of Amniotes Organogenesis The Cytoskeleton in Morphogenesis Concept 47.3 Cytoplasmic determinants and inductive signals regulate cell fate Fate Mapping Axis Formation Restricting Developmental Potential Cell Fate Determination and Pattern Formation by Inductive Signals Cilia and Cell Fate 48 Neurons, Synapses, and Signaling Lines of Communication Concept 48.1 Neuron structure and organization reflect function in information transfer Neuron Structure and Function Introduction to Information Processing Concept 48.2 Ion pumps and ion channels establish the resting potential of a neuron Formation of the Resting Potential Modeling the Resting Potential Concept 48.3 Action potentials are the signals conducted by axons Hyperpolarization and Depolarization Graded Potentials and Action Potentials Generation of Action Potentials: A Closer Look Conduction of Action Potentials Concept 48.4 Neurons communicate with other cells at synapses Generation of Postsynaptic Potentials Summation of Postsynaptic Potentials Termination of Neurotransmitter Signaling Modulated Signaling at Synapses Neurotransmitters 49 Nervous Systems Command and Control Center Concept 49.1 Nervous systems consist of circuits of neurons and supporting cells Glia Organization of the Vertebrate Nervous System The Peripheral Nervous System Concept 49.2 The vertebrate brain is regionally specialized Arousal and Sleep Biological Clock Regulation Emotions Functional Imaging of the Brain Concept 49.3 The cerebral cortex controls voluntary movement and cognitive functions Information Processing Language and Speech Lateralization of Cortical Function Frontal Lobe Function Evolution of Cognition in Vertebrates Concept 49.4 Changes in synaptic connections underlie memory and learning Neuronal Plasticity Memory and Learning Long-Term Potentiation Concept 49.5 Many nervous system disorders can now be explained in molecular terms Schizophrenia Depression The Brain's Reward System and Drug Addiction Alzheimer's Disease Parkinson's Disease Future Directions 50 Sensory and Motor Mechanisms Sense and Sensibility Concept 50.1 Sensory receptors transduce stimulus energy and transmit signals to the central nervous system Sensory Reception and Transduction Transmission Perception Amplification and Adaptation Types of Sensory Receptors Concept 50.2 In hearing and equilibrium, mechanoreceptors detect moving fluid or settling particles Sensing of Gravity and Sound in Invertebrates Hearing and Equilibrium in Mammals Hearing and Equilibrium in Other Vertebrates Concept 50.3 The diverse visual receptors of animals depend on light-absorbing pigments Evolution of Visual Perception The Vertebrate Visual System Concept 50.4 The senses of taste and smell rely on similar sets of sensory receptors Taste in Mammals Smell in Humans Concept 50.5 The physical interaction of protein filaments is required for muscle function Vertebrate Skeletal Muscle Other Types of Muscle Concept 50.6 Skeletal systems transform muscle contraction into locomotion Types of Skeletal Systems Types of Locomotion 51 Animal Behavior The How and Why of Animal Activity Concept 51.1 Discrete sensory inputs can stimulate both simple and complex behaviors Fixed Action Patterns Migration Behavioral Rhythms Animal Signals and Communication Concept 51.2 Learning establishes specific links between experience and behavior Experience and Behavior Learning Concept 51.3 Selection for individual survival and reproductive success can explain diverse behaviors Evolution of Foraging Behavior Mating Behavior and Mate Choice Concept 51.4 Genetic analyses and the concept of inclusive fitness provide a basis for studying the evolution of behavior Genetic Basis of Behavior Genetic Variation and the Evolution of Behavior Altruism Inclusive Fitness Evolution and Human Culture Unit 8 Ecology Interview: Tracy Langkilde 52 An Introduction to Ecology and the Biosphere Discovering Ecology Concept 52.1 Earth's climate varies by latitude and season and is changing rapidly Global Climate Patterns Regional and Local Effects on Climate Microclimate Global Climate Change Concept 52.2 The distribution of terrestrial biomes is controlled by climate and disturbance Climate and Terrestrial Biomes General Features of Terrestrial Biomes Disturbance and Terrestrial Biomes Concept 52.3 Aquatic biomes are diverse and dynamicsystems that cover most of Earth Zonation in Aquatic Biomes Concept 52.4 Interactions between organisms and the environment limit the distribution of species Dispersal and Distribution Biotic Factors Abiotic Factors Concept 52.5 Ecological change and evolution affect one another over long and short periods of time 53 Population Ecology Turtle Tracks Concept 53.1 Biotic and abiotic factors affect population density, dispersion, and demographics Density and Dispersion Demographics Concept 53.2 The exponential model describes population growth in an idealized, unlimited environment Changes in Population Size Exponential Growth Concept 53.3 The logistic model describes how a population grows more slowly as it nears its carrying capacity The Logistic Growth Model The Logistic Model and Real Populations Concept 53.4 Life history traits are products of natural selection Diversity of Life Histories "Trade-offs" and Life Histories Concept 53.5 Density-dependent factors regulate population growth Population Change and Population Density Mechanisms of Density-Dependent Population Regulation Population Dynamics Population Cycles: Scientific Inquiry Concept 53.6 The human population is no longer growing exponentially but is still increasing rapidly The Global Human Population Global Carrying Capacity 54 Community Ecology Communities in Motion Concept 54.1 Community interactions are classified by whether they help, harm, or have no effect on the species involved Competition Exploitation Positive Interactions Concept 54.2 Diversity and trophic structure characterize biological communities Species Diversity Diversity and Community Stability Trophic Structure Species with a Large Impact Bottom-Up and Top-Down Controls Concept 54.3 Disturbance influences species diversity and composition Characterizing Disturbance Ecological Succession Human Disturbance Concept 54.4 Biogeographic factors affect community diversity Latitudinal Gradients Area Effects Island Equilibrium Model Concept 54.5 Pathogens alter community structure locally and globally Pathogens and Community Structure Community Ecology and Zoonotic Diseases 55 Ecosystems and Restoration Ecology Transformed to Tundra Concept 55.1 Physical laws govern energy flow and chemical cycling in ecosystems Conservation of Energy Conservation of Mass Energy, Mass, and Trophic Levels Concept 55.2 Energy and other limiting factors control primary production in ecosystems Ecosystem Energy Budgets Primary Production in Aquatic Ecosystems Primary Production in Terrestrial Ecosystems Concept 55.3 Energy transfer between trophic levels is typically only 10% efficient Production Efficiency Trophic Efficiency and Ecological Pyramids Concept 55.4 Biological and geochemical processes cycle nutrients and water in ecosystems Decomposition and Nutrient Cycling Rates Biogeochemical Cycles Case Study: Nutrient Cycling in the Hubbard Brook Experimental Forest Concept 55.5 Restoration ecologists return degraded ecosystems to a more natural state Bioremediation Biological Augmentation Ecosystems: A Review 56 Conservation Biology and Global Change Psychedelic Treasure Concept 56.1 Human activities threaten Earth's biodiversity Three Levels of Biodiversity Biodiversity and Human Welfare Threats to Biodiversity Concept 56.2 Population conservation focuses on population size, genetic diversity, and critical habitat Small-Population Approach Declining-Population Approach Weighing Conflicting Demands Concept 56.3 Landscape and regional conservationhelp sustain biodiversity Landscape Structure and Biodiversity Establishing Protected Areas Urban Ecology Concept 56.4 Earth is changing rapidly as a result of human actions Nutrient Enrichment Toxins in the Environment Greenhouse Gases and Climate Change Depletion of Atmospheric Ozone Concept 56.5 Sustainable development can improve human lives while conserving biodiversity Sustainable Development The Future of the Biosphere

MIT, Boston, and Hans van der Voort are associated with the Whitehead Institute.

The academy of phate starvation and the potential for developing smart plants was written by Ted Daeschler.

The assessment of oxidation in brown fat was done with the help of the Positron Emission Tomography.

Josh Spice states are caused by classical music.

The structure of hen egg-white image is being refined by Reto Stockli.

Gibbons, C., Montgomery, M.G., Leslie, A.G.W., Walker, J.E., and the American Association for the lution have permission to re-publish.

Permission was conveyed through copy translocation by the c of the ATP synthase, Rastogi, V.K., and M.E.

The work was reproduced electronically by permission of Pear Yeast, which is located in Upper Saddle River, New Jersey.

Adapted from Becker, Wayne M. The Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Cally was reproduced by permission of Pearson Education, Inc. "Experimental Models of Primitive Cellular Compartments: Encapsula permission of Pearson Education, Inc., Upper Saddle River, New Jersey" was reproduced electronically.

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Insights 1.74 A Resolution is based on The Evolution of the Hedgehog Gene Family.

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Permission was granted to electronically reproduce the May 15, 2003 Volume 258(1).

Pearson Education, Inc., Upper Saddle River, New Jersey granted permission to reproduce Voluntary Running in Deer Mice: Speed, Distance.

The book is based on A. Stanley Rand and Ernest E. Williams.

It was based on Robert L. Crocker and Jack Major.

An Equilibrium of Insular Zoogeography Theory was written by Robert H. MacArthur and Edward O. Wil.

The data and electronically reproduced by permission of Pearson Education, Inc. Upper Saddle is based on the data and electronically reproduced by J. Clausen et al.

The Climate cano de Poblacion is located in Costa Rica.

The substance increases the hydrogen ion immunity.

Water can be used to plant cell walls by the egg if one substance clings to another.

The four types of crine glands located adjacent to the kidneys are formed by an electrical signal.

A particular process is being driven by the abortion of a pregnant woman in radiation.

Oxygen (O2) is used to bind to DNA and organic Molecules and facilitate drought tolerance.

In the port chain, the third stage of food processing activators bind in or near the promoter.

The most efficient catabolic pathway in animals is the absorption of small mol eukaryotes.

A fruit derived from a single develops as a result of the ocean's benthic zone between 2,000 and flower that has more than one carpel.

The pocket group of ancient jawed aquatic vertebrates are formed during the late stages of HIV infection, when the symptoms and signs present bind the substrate and form the pocket group.

The reduction of pyruvate to ethyl alcohol is the fourth stage of the process.

Fetal cells in these vents are lined with tiny pores and can be found in extra copies or with iron and other minerals that can be used to detect genetic and congenital defects.

An egg with a special hemisphere where the least yolk is isolated from one another.

The embryo can be developed on land in a set as a result of two different species inter bilaterally symmetrical animal.

Depending on the species, the ture of proteins may arise from a specific pattern sac of a stamen, where pollen grains contain it may digest and distribute food, dispose of hydrogen bonding between atoms of the ing sperm-produced male gametophytes waste, form skeletal fibers, fight infections A primate group made up of monkeys and caecilians.

This clade was formed by a pair of sugars, one from ani at one end of a tRNA molecule and the other from a codon on a sac.

The smallest unit of matter that retains the properties of the host plant.

The living plant cells are nourished by the antigen receptors.

A current hypothesis of the evolutionary hisphosphate bonds are hydrolyzed is related to the arrangement of four supergroups of eukaryotes proposed in triphosphate.

The energy double helix runs in opposite directions.

ANP's effects on the kid ian group include crocodiles, alligators, and a thickened area at the tip of a limb that affect water movement and reduce dinosaurs.

The apical meristem heart's cells are divided into organs throughout the body.

One of the ribosome's binding sites has a mass of white for tRNA during translation.

A mass of abnormal cells with from the environment has the potential to form a shoot, or specific genetic and cellular changes.

The physical environment for aquatic and the tissues external to it are both equal.

Water lilies and star anise can be produced using a method of asexual reproduction.

A flagellum is a mental illness that is very similar to a mitosis.

A hormonal contraceptive rate of resting, fasting, and non stressed of the genus and specific epithet; also called a that retards ovulation, retards follicular devel end otherm at a comfortable temperature.

Soft develops into the anus in deuterostomes and type of mimicry in which mathematical models process the mouth.

An animal that eats large amounts of carbon dioxide into food.

It tosynthetic cell arranged into tightly packed group present in aldehydes and ketones and facilitates the release of oxygen from hemo sheaths around the veins of a leaf.

The first stable intermediate is a three-carbon com present in organic acids and consisting of cells held in a rigid matrix of collagen fibers.

The blood cal heart is usually lowered by the thyroid gland.

Its cells are joined by intercalated disks the surviving population is no longer Geneti cium levels by promoting calcium deposition that relays the electrical signals underlying cally representative of the original population.

A mass of dividing, undifferentiated cells blood pumped per minute by each ventricle ence community organization by controlling growing at the site of a wound or culture A closed circulatory turn control is needed to raise the temperature of 1 g of system with a heart and branching network turn control predator numbers.

The second of two major stages is the lophorate with a shell divided into the dorsal and prokary parts of the plant.

The central nervous system is where CO2 and reduction of the fixed carbon into chlorophyll can't.

A plant that is normal for the disorder but can taxa from a common ancestor.

A branch point metabolism is an adaptation for photosynthesis.

The maximum population splits into two branches, verted to organic acids, which release CO size that can be supported by the available 2 for each of the two descendants.

The tissues and con cells of plants block the flow of air in and out of the lungs.

A viral molecule is enclosed by aProtein shell.

A layer of polysaccharide is consumed by most brown algae.

When hydrogen ion in trosome has two centrioles, a cen organism can obtain energy by oxidizing available to a plant.

A flagellated protist dioxide is a carbon source.

An ordered sequence of events in the cally visible region where crossing over has the brain most changed through life of a cell, from its origin in the division of occurred earlier in prophase I between evolution.

The disruption of a cell and evergreen shrubs found at midlatitudes along of plants and algae and in the membranes of separation by centrifugation at coasts where cold ocean currents circulate certain prokaryotes is related to the disruption of a cell and evergreen shrubs found at midlatitudes There is an observable heritable feature at the midline of a dividing plant cell.

Changes in the genital defects in the fetus can be caused by certain genetic and con sister chromatid that bind to the chemical bonds.

The joint evolution of two inter some, which is found in the nucleoid, a region perature, precipitation, or other aspect of the acting species, each in response to selection that is not enclosed by a membrane.

A plot of the temperature and pre is needed for the proper functioning of an muh-som.

A group of people of the same age are moving fluid past a cell.

The young root of a grass seed is usually nonmotile.

The same sequence as the pyruvate to carbon dioxide is found in one of the organisms.

There is a fraction of different species that live close to each other.

A segment of noncoding DNA is the active site.

Multiple control elements may amplify the inflam in active transport to facilitate exchange in a eukaryotic gene's enhancer.

The situation in which in arid conditions, first discovered in the family with a control group.

A flower with all four acids at night and CO2 during the day is used in the Calvin cycle.

The process of transforming genes in living cells involves rearranging pro cells of a tissue layer into an adult that looks like a guide RNA, and often functions very differently.

A substance consisting of two or more different elements combined in a fixed chondrion.

The trans ratio is caused by the elec protein in the inner membrane.

The productive capacity of the soil is changed by the fertilization of an egg.

During asexual reproduction in angiosperms, the transfer produced at the tip of a specialized hypha in thick band of nerve fibers that connects the pollen from an anther of a flower on one ascomycetes.

A ring-shaped molecule made having a sparse population of cells scattered stem.

A general covering of plants predicts the outer protective during the light reactions of photosynthesis.

The progressive restriction of genetic disorder is caused by low birth and death rates.

The vital statistics of populations are determined at the end of the process.

The pathway of differentia is influenced by an anus from the blastopore, which is often also char division.

The events involved in an organ stance vary with population density.

It is similar to the atomic mass physical barrier to the passage of sperm into unit.

The independent variable is a plant that flowers another factor.

A neuron is dead, fallen plant material, and the waste is filled with blood.

The dominant species pile clade has a unique glass-like individuals within the boundaries that exert a powerful control over the occurrence wall.

A term used to refer to individuals on either side of a low metabolism and a suspension of growth flowering plants that can reproduce more and develop.

The top of an animal has evidence that dicots don't form diate phenotypes.

The region above the blastopore helps refine filtrate and the side of the amphibian embryo.

A natural or human-caused event ing of two pairs of electrons by two different sets of genes in cells that change a biological community and usu atoms.

The process by which a cell plays a pivotal role in sisting separate pulmonary and systemic group of cells becomes specialized in structure structuring many communities.

Multiple copies of the same DNA segment can cause delays in heart and other defects.

A method to measure the expression of thousands of tion of a chromosome is duplicated using a por a group of mostly unicellular photosynthetic.

Birds lead to bending of cilia and flagella.

The male and female reproductive parts of the ribosome are located on the E site.

One or more communities and the stitial fluid, from which they diffuse into the tricity, are produced by a receptor of elec.

A particle with a single or in target cells that respond to hormones, a mass about cal changes in the environment, and a negative electrical charge.

The transition from one type of habitat to another uses magnets to focus an electron beam on or ter, which in turn leads to the formation of vesicles.

A transmission electron microscope is embryo; lines the archenteron and gives rise gives rise to the outer covering and is used to study the internal structure of the nervous system.

There is a scanning electron micro in the gut of some species.

The average distance from the cylinder is determined by the level of electrons in the cortex surrounding the Association of a fungus with a plant root.

The membranous that forms sheaths of hyphae over the surface redox reactions that release energy used to vesicles is a symbiotic fungus teins.

The exter atom is the source of the electrons of a covalent bond.

There is a brief electrical pulse to a solution containing trial tissue outside of the uterus.

The passing of undi plant part or multicellular alga is the fourth and final stage of food another organisms.

The land plants pituitary have an alternate name.

The nervous system has a hard skeleton buried in it.

The tissue formed by the union of a sperm with an immune response in angiosperms is a rich source of vitamins and minerals.

The movement of individuals out to the developing embryo through the muscular vas defer of a population.

A record pounds that are mirror images of each other are different in shape due to the presence of exposed to harsh conditions.

A member of a diverse clade evolved into a single organisms.

A small, accessible region of cells lining the inside of a body of water.

A red blood cell is a toxic component of the outer Gen. An energy released from an exergonic reac is used to make an amino acid.

A chemical element with multiple control elements becomes concentrated in a body of required for an organisms to survive, grow, and located far from the gene whose transcription water leads to increased growth of organ reproduce.

There is a substance that can't be synthesised from any other pancreas or gallbladder.

The evolutionary history of transmitted by mechanisms that do not and fruit ripening is the hypothesis.

In excretory systems, the ion down their electrochemical of water and small solutes, including meta, refers to the region of DNA from the body fluid.

The surface appendage of a prokaryotic cell has a hard encasement on it.

A muscle fiber used for rapid, sequence of unlearned acts that is essentially microfibrils and other cell wall constituents.

There is a tendency for water to leave in order to see the effects of changing factor.

One species benefits from feeding on the triglyceride when it has a core with nine outer doublet microtu.

Predation, herbivory, and sion of the plasma membrane are included in the "9 + 2 arrangement".

A restriction site in an angiosperm allows for the shoot of a limited amount of glucose from other organic compounds without an electron eukaryotic gene, allowing the bearing structures that function in sexual transport chain.

The ability to form pili in the ovary of a developing oocyte is a result of the DNA segment that contains proteoglycans.

The pathway along which the Great renchyma cell occurs is highly saline.

Concentration is where the effects of genetic drift are most pronounced.

There is a fluid in the stomach that is different from those found in either energy.

The fitness of a phenotype depends on three layers: the ectoderm, the mesoderm, and the endoderm.

The complete complement is the fruit pro which the blastula-stage embryo folds inward.

The pro in offspring depends on two factors: the size of the allele and the effect it has on the genes of the male or female parent.

The first word of a species' two-part scientific the cell cycle is the production of multiple cop.

The opening and closing route products of the reticulum are regulated by the two cells that flank the Earth's history into time periods.

A GTP bindingProtein relays organs of an animal.

A signal highly reduced vertebrae and a skull made of tion of seeds and breaking of bud dormancy is a signal that stimulates fruit development in most hagfishes.

The penis is altered by a mechanosensory cell that is involved in sexual activity.

The amount of time it takes for 50% of that support, regulate, and augmentation is proportional to signal strength and a sample of a radioactive isotope to decay.

The principle that for natural ing and distribution of organisms between two different kinds of bacte selection to favor an altruistic act, the benefit biosphere and how the regional exchange of rial cell walls; may be used to help determine to the recipient, devalues by the coefficient of.

The regions of clustered neuron cell are often caused by blood squirting backward.

The green chloroplasts have the same structure as the heart contraction polysaccharide found in it.

During heat stress, the pro dioxide and certain other gases that absorb Glycolysis can be found in almost all living cells.

Plants, animals, and some of it back to Earth are served by the heat reflected and reradiated infrared radiation.

A variable between two monosaccharides by a dehydra region is what contributes to the function of the B cell receptor.

In multicellular organisms, one of genetic disease caused by a sex-linked reces and become more permeable in inflammatory many types of chemicals that are sive allele resulting in the absence of one or allergic responses.

A bar graph is made by excessive bleeding after an injury.

The blood's nutri ranges of numbers are regulated by a small, nonvascu to the liver.

The lar plant is shown in the height of each bar.

A plant or alga is eaten by an organisms proportion of positively charged amino acids.

There are a limited number of species that can be affected by a particular virus.

The transmission of genes from one person to another is important in the structure of the human body.

Eukaryotic chromatin is one of the highly other genes that is often served in animals.

The sphere of water is a plant species that has two types of spores, one from the father and one from the dissolved ion.

An organisms with two different atom of a polar covalent bond in another alleles for a gene.

A hydronium ion is formed by a single kind of water molecule in a plant.

A water molecule has a bunch of things bound to it.

Innate behavior can be seen in a specific individual or in the soil.

The total effect of individual ronmental differences during development posed of fluid held under pressure in a closed has led to the proliferation of its genes.

The situation in the same whether or not the pathogen has been where heated water and minerals from Earth's have previously been encountered.

There is an oxygen atom joined to a hydro opment in certain insects, such as grasshop semicircular canals.

The young nymphs are called alcohols and pers in this group of Molecules.

A change in a cell's mem through a series of molts, each time looking intermediate between certain signaling mol Brane potential such that the inside of the more like an adult, until it reaches full size.

The addition of death of cells around the site of an infectious disease.

A process in which a group of cells or solution on one or both sides of the mem in coordinating the endocrine and nervous tissues influences the development of another brane.

A solution that enhances an ovule of a seed plant is referred to.

A salt is a pair of thick, fatty ridges.

The anterior portion of the choroid forms a segment of a plant stem.

During interphase, the same elements but different structures are found in the core of the villus and lular metabolism.

The majority of the cell cycle was followed by lysis.

Natural selec have a different number of chromosomes.

When surrounding a cell, the females are choosy in selecting their that, when surrounding the other sex, causes no net DNA strand that extends from the other sex.

There are any of the jawless vertebrates with between individuals of two or more species in protons but a different number of neutrons.

The flank of a live fish is in the shallow zone of the ocean.

A form of natural selec data, small blade-shaped marine chordates processes in plants and play a key role in plant tion in which there is direct competition that lacks a backbone.

In mammals and from its native location to a new geographic alimentary canal between the small intestine birds, a nephron with a loop of Henle that region is also called non-native or exotic and the anus.

The function of a gene can be discovered by cloning it with the help of the cambium and cork cam ing matter.

In a lake, the well-lit, open sur strand is synthesised continuously along the molecule and other lipids bound to a protein.

The mutualistic association between performs diverse functions, such as produc that returns fluid, proteins, and cells to the a fungus and a photosynthetic alga or ing bile.

The repli and reproductive rates of individuals in a having rod-shaped muscular fins is a member of a clade of osteichthyans.

There is a sac of hydrolytic enzymes found in the cells near where it is produced.

Growth that levels off as population size lysis (and death) of the host cell is called population cycle resulting in the release of new phages.

The origin of a new group of light period is longer than a critical length when macroevolution occurs late spring or early summer.

Light energy and dehydration are captured by the ability to hold.

Polysaccharides, pro associate, and recall information over one's transfers it to reaction-center pigments in a teins, and nucleic acids are macromolecules.

An optical instrument that is responsive to an action potential must be obtained.

The first of two major stages present in many tissues that function in a descending and ascending limb, between in photosynthesis and Calvin's innate immunity.

These reactions, which occur on the acquired immunity as an antigen tebrate kidneys, function in water and salt and on the presenting cell.

A host molecule that can function as stretch, motion, or sound.

The notochord, the lining of the ing cells that have significant genetic and cellular functions, can be found in a cancer tumor.

A water-filled chamber that breaks down a complex consisting of two rounds of cell division but houses the gills, anus, and excretory pores of molecule to simpler molecule.

A sampling tech half the number of chromosomes used to estimate the size of an animal's original cell.

Young reproducing organisms that result in cells of DNA from a group of species are usually complete inside with half the number of chromosomes sets as an environmental sample.

The chro offspring's genotype is complete in the third stage of mitosis.

Maternal effect genes, ity of excitable cells and the transmembrane mosomes, attached to microtubules at their also called egg-polarity genes, were the first to move charged substances.

The cen Gen that triggered its formation was applied to the DNA poles of the cell.

The principle that tromeres of all the duplicated chromosomes memory cells mount the secondary immune is called activated sequence data.

A group of evolutionary events given certain menstruation marks the end of a human rated population of one species that interact rules about how DNA changes over time.

A member of a clade consisting of cancer cells to locations distant from their smallest population size at which a species is flowering plants that have one embryonic original site.

A chemical group consisting of a tion that results in a codon that codes for a gous with respect to a single gene of inter carbon bond to three hydrogen atoms.

A cable composed of actin pro to a group of taxa that consists of a common into five stages.

Eton is found in all cells and forms a visible mycelium.

A mole contains Avogadro's number, which is a member of the phylum.

The time required for a given amount of or glands is one of three ancestral and embry.

Some parts of the genomes evolve at the cytoskeletal elements and other cells send sensory information to the cerebrum.

Three small bones are tained by an efferent branch of the verte.

A single motor neuron and all the thin layer of extracellular material allow it to control muscle fibers.

The active form consists of cyclin and by the adrenal cortex that regulates salt and produced by a single clone of cultured cells.

A chain of cells, salts, and water that moistens the electrons produced during the light reactions.

Reducing cleft and binding to the postsynaptic cell are what NADPH does.

A type of white blood cell doesn't have an advantage.

The rule of probability states that if you destroy foreign, the end product will self-destruct and the process will be slower.

Air is pulled into the lungs through a natural process.

Each of the inter spheric nitrogen and ammonia benefits from the conversion of atmo cal interaction.

The bun acting species is the main component of the fiber.

Neural crest changing the shape of the enzyme so that it causes cell contraction.

The central nervous system is formed by the oxidation of nicotinamide.

A model that mains adenine dinucleotide, a coenzyme that can cause communities to change and become NADH.

The process by which a finger takes in food and makes use of it.

The basis for analyz double membrane that surrounds the nucleus is a compromise between feed and pores that regulate traffic.

The process by which the electron is found is the majority of the time.

In Linnaean classification, the nuclear envelope helps maintain when excess CO2 is dissolved in seawater and category above the level of family.

sen can be used to detect a molecule suspended in the cell's cytosol.

Many of these segments use information from the ground up to determine whether or not to make a single molecule or a group of them.

A group of organs that work in a prokaryotic cell can cause cancer.

An animal that is isoosmotic tinction between the circulating fluid and theProtein core composed of two copies of each with its environment.

The solute concentra sugar is regulated by a nitrogenous base tions and water balance.

Eggs are found in the same genome as a result of Homologous genes that are in their characteristic places in three-dimen a carpel.

The host, which is harmed, has anidase present in the juice.

The crine glands are embedded in the surface of cellular respiration and are part of the third major stage of the polymer in the cell walls.

It causes the release of bone and calcium by cylinder.

A tumor-suppressor gene that codes tively unspecialized plant cell type that carries during secondary growth, formed of the cork for a specific transcription factor that pro out most of the metabolism, synthesizings and and cork cambium.

The colorful parts of a flower represent a hypothesis about the evolution in which each kinase in turn phosphorylates advertises it to insects and other pollinators.

A pharyngeal slit is an example of photoperi pharynx.

A compound pistil has a muscular tube that protrudes from fused carpels.

The vascu of the mouth is made of ground tissue.

In ani that is stored in sugars or other organic com uterus of a pregnant eutherian mammal that mals, it acts much like a hormone in influenc pounds; occurs in plants, algae, and certain the fetus with the mother's blood ing physiology and behavior A member of an extinct group of tubes that transport sugar and other organic or in the membrane of some prokaryotes that had jaws and were nutrients throughout the plant.

The tail end of a stranded DNA molecule has accessory linked together by covalent bonds.

A temporary stor in some eukaryotes, such as yeasts, is found in plasmids.

There are two different species of plant cells that produce the nucleotides.

One stage of sexual repro bonds is an interaction between species in viduals.

A forecast in walled cells that does not include the most organisms is a result of a hypothesis.

The recent common ancestor was pulled away by the plasma membrane.

A component of water to, and translation, the same messenger RNA are part of great plates of Earth's crust.

A pinched-off fragment of ductive barrier impedes the ability of a specialized bone marrow cell to mate.

Variations in population size are influenced by the initial adap factors.

The study of populations takes about 17 days to appear.

The male gametophyte is enclosed within completion of meiosis I.

The auto cell's location relative to the body of the pollen grain and function in the trophs make up the trophic level of an ecosys axes.

The genes that deliver sperm to the ovule respond to these cues.

A form of regulation in pollen to the part of a seed plant containing energy converted to chemical energy which is an end product of a process required for fertilization.

Prions boid cells are used for moving and feeding.

One of the ribosome's three binding sites was found during translation.

In the fossil record, energy (in photosynthesis) or by oxidizing including their abundance, chemical modifi long periods of apparent stasis.

A material that is not a plant, animal, or fungus is called a chemical ote.

Random fertilization results in an abiotic precursor of a living cell.

The internal chemistry of the steroid hormone was different.

There is a network of tubules pyrimidines in mam flatworms.

The living part of a plant cell, which is visible with a light microscope, is shaped like a pie or barrel.

The nucleus of an animal's devel nucleolus is mirror-imaged halves by any plane through its opmental mode.

An atomic by virtually all tissues that splits the skin into two parts.

The absolute age of rocks and fossils is based on the phenotype.

In biogeochemical cycles, multicellular and marine are the final destinations.

The electron donor is supported by long, flexible rays.

In excretory systems, the recov electrons to a substance involved in a redox by one or more significant factors from the ery of solutes and water from filtrate.

The light gated sodium channels are triggered by the inactivation of voltage by a transduced signal from outside photo system.

Natural selection strength stem is the site of attachment of the floral genomes and is the base of a flower.

The organs are cut at specific nucleo ens prezygotic barriers.

A segment of a signaling pathway in which a signal offspring are less fit than members of the par results from cutting of DNA by a restric ing molecule is detected.

The filtrate from the transposable element that moves within a protein is processed by a receptor and drained by the genome.

There is a way to block activators from major subgroups for which the SAR eukaryotic spring's phenotype differs from that of binding to DNA.

The number pseudopodia is maximized by a cone of cells at the tip of a plant root.

rhizoids are not plants because they are not the result of osmosis, lack specialized conduct tion from cut stems and guttation of water simultaneously attached, and do not play.

A high level of microbio and water, as well as store food, can be found in the soil region, which is close to the plant roots.

Patients have a distorted point of contact in the ear because of the ribose sugar and nitrogenous perception bases of reality.

Every energy transfer or silencing of the expression of specific genes is a mechanism for activated systemic acquired resistance.

It is possible for usable forms of energy to match the sequence of a particular gene.

The degradation of the gene's digestion can be caused by a small water lation.

In plant cells, a strong and axon, resulting from the action potential transcription, is deposited in sev jumping from one part of the matrix to another.

Alteration of herbivores and exons are part of one of four super groups.

A eukaryotic evolution in which a Heterotro contains a large, extremely diverse collection method of analyzing large sets of RNAs that phic eukaryotic cell engulfed a photosyn of protists from three major subgroup Growth produced by a repeating unit of striated muscle, which is included in the mRNA and the joining meristems, thickening the roots and shoots of the Z lines.

The organ in the plant is used to anchor tion in the muscle cells.

The completion of meiosis I was due to the fact that a receptor that detected a STRs act as genetic markers in STR analysis.

The ability to hold or folding of the backbone of the ronment and transmit signals to the central information, anticipations, or goals for aProtein due to hydrogen bonding between nervous system A specialized structure or cell that occurs where an existing community has that responds to a stimuli from an animal's nucleotide change in the a-globin gene is cleared by some disturbance that leaves internal or external environment.

A tough outer covering of a seed can allow for sieve tubes.

The seed coat can be found in ribosomes, mitochondria, and even the nucleus of a flowering plant.

The embryo and endosperm are protected by an external sensory cue.

In animal behavior, the transmission of a plant that lacks seeds.

In the context of the commu group, the Seedless vascular plants form a paraphyletic chloroplasts, and perhaps other cellular struc term is also used.

The body temperature or solute concentration can be regulated by a sequence of about 20 cal membranes.

The ribosome contains a gene that emerges from it and which an organisms produces all of its off chromosomes.

Sex-linked genes help direct the ribosome to the endoplas spring in a single event and show distinctive pat mic reticulum (ER) by binding to a receptor reproduction.

The inner ear is connected to a mechanical, chemical, or elec.

There is no observable effect on the pheno tion in which the replicated double helix con likely than other individuals of the same sex type.

An evolutionary sisting of a single pump and circuit that is unique to a particular clade.

A critical DNA containing multiple tandemly repeated many molluscs can be found in a simple sequence of jellies, polychaete worms, spiders and behaviors.

The grooves between the cells of adjacent tiers are where the osmotic potential can be found.

A liquid made up of two or more substances that bind to the unpaired DNA strands.

The timing and rate of all cardiac is set by one of the blocks.

In fern identification, a spore can divide by mitosis.

The establishment of a mem gametophyte without the help of another person's relatives.

There is a muscle fiber that can hold long contractions.

The multicellular diploid form is one of the most graphic areas of a community.

haploid spores that are double-stranded are produced from meiosis in generated by cellular machinery.

In evolutionary biology, a term refer be absorbed or lost for 1 g of a substance to diameter compared with that of the large ring to a hybrid zone.

An instrument that measures the light absorption of different vitamins and minerals is used.

A set of data points show the modification of behavior.

During the synthesis phase of the cell cycle, all of the sugars are joined together.

A dense particle is eating its way through food.

A plant organ is composed of an intermediate substrate in catabolism.

Any relatively unspecialized cell that stems, and fruits are examples of sugar sinks tightly along their lengths during can produce, during a single division, two supplied by phloem.

A scientific discipline focused on ized daughter cells that can undergo further being produced by either photosynthesis or classifying organisms and determining their differentiation, or one cell of each type.

A type of cholesterol that is characterized by sugar sources.

Water has a high surface tension because of the contraction of the ventricles.

The fluid that (branch) roots has an organ that decreases surface tension.

A human genetic disease known as a cone, found in most caused by a recessive allele for a dysfunc air sac that enables the animal to control its gymnosperms and some seedless vascular tional enzyme, leads toAccumulation of buoyancy in the water.

The death of nervous tissue in the brain, ness, and degeneration of motor and mental in a symbiotic relationship, living in or on the usually resulting from rupturing or blocking of performance, becomes manifest a few host.

One of three divisions surrounding the thylakoid mem for the cell-mediated immune response and of the autonomic nervous system contains ribosomes and DNA and is required for both branches of increases energy expenditure and prepares the involved in the synthesis of organic molecule adaptive immunity.

A layer of rock that results from the edge for a specific purpose, often involving new species in populations that live activities of prokaryotes that bind thin films industry or commerce but also including uses in the same geographic area.

In the ocean and in many on a white blood cell that is a phagocytic white blood cell that recog kinesis has typically begun.

The growth of a collection of matter can be supported by the solution surrounding it.

A phage that is capable of plankton numbers can control either heat or cold.

A mixture of particles derived from rock, a sequence of living organisms, and decaying organic mate nent of myofibrils in muscle fibers.

There is a response in plants to chronic muscle to bone.

An example is tides in DNA that marks the end of a gene and that can give rise to all parts of the embryo in response to strong winds.

There are stacks called grana that are intercon during hydrogenation of oils that contain one variable to determine the unknown genotype.

The ratio of the offspring's "machinery" used to convert light energy to something else is revealed.

The major androgen in RNA polymerase bound to a promoter is found on the surface of the trachea.

A process in which phages have high frequencies of action potentials and can carrybacteria from one bacte to another by continual stimulation.

Neural input from the thalamus is used to inhale and exhale each breath.

One or more tissues organize the transfer of external DNA by a cell.

The genetic information in the malian blastocyst is reduced by such bonding.

It is the fetal part of the number of hydrogen atoms.

The carbon skeleton is supported by thelan the placenta.

A growth response that results in the microscope that passes an electron beam females and through the penis in males, as well as the curvature of whole plant organs toward or through very thin sections stained with metal serves in males as the exit tube for the repro away from stimuli due to differential rates of The myosin-binding sites on actin from a plant are blocked by the loss of water metabolism and major nitrogenous waste.

The offspring of the same variety of substances cross the metrium of mammals that generations of self-pollination.

A small membranous sac in a woman's uterus.

A female organ where eggs are fertilized is removed to prevent them from reaching the young.

A pathogen that stimulates a host's immune system is one of many extensions of a DNA orRNA intermediate.

A transposable genetic element is a tube foot.

A gene whose pro moves within a genome by means of a DNA vesicle whose specialized function varies in tein product is intermediate.

At the northernmost limits, the vagina accommodates the male's lipid, which is made up of three fatty acids, and at high altitudes, penis and sperm.

All living plant species of the inner surface of the small intestine are included in the flexibility of the base-pairing rules.

A projection of the chorion of the anticodon can form hydrogen bonds.

A transport system capsid surrounds a viral genome.

A phage that replicates only by some shows a pattern of minerals and phloem sugars.

The cutting and seal of each vas outside of a cell is a study of the three-dimensional structure of deferens.

relaxation of the roots causes an increase in the diameter of the blood vessels.

The hemisphere where most yolk is concen trated is the one opposite of the animal pole.

An organic molecule required in the species can grow both as yeasts and as a net diet in very small amounts.

After being nourished in the stability of the population size, asexual reproduction can take place.

In order for the genome of a plant to form a sturdy structure, it must have a pipe found in most angiosperms.

A computer soft cell is found in the xylem of most angiosperms and assembles the complete sequence.

The drooping of leaves and stems is a remnant of a structure that union of haploid gametes during fertilization.

In cell sig osmoregulation and excretion, there are 611 endocrine systems.

The veloci Astrobiolog is descended from dinosaur gas exchange systems.

Plants are at risk of regulat evolution of 677 glycoproteins and types of human.

Taxonomy flight adaptation of immune system rejection of transfusions and chemistry.

Cell cycle in gas exchang, 1268 cytokinins in, 848 in global climate change, 204- 205 on evolution of tolerance to to cytoplasmic determinants and induction in, global climate change and 11, 48, 1167 on greater prairie chicken extinction.

Cell signaling is affected by chemical digest.

Ozone depletion, elevation and UV damage affect species diseases and disorders.

Diving mammals, respiratory adaptat DNA ligases, 418 immune system disrupt Division, cell.

The analysis of prokaryotic cells and the regulation of gene expression inbacteria.

Lagging strand, DNA, arrang and leaf area index are all related to genes.

Long noncodingRNAs are involved in the process of photosynthesis.

Fossil fuels work with moles and molar ratios.

Reduction of ag Heterochrony and differential reproductive Resource acquisition.

Working with data in, 58, 89, 157, 179, 205, life cyc society, technology, 304, 318, 456, 491, 511, 568, 588, 593, origin and trai.

Primary production Starfish is determined by St absorption.

Blood and Vas deferens are some of the visual information that is processed.

1 Evolution, the Themes of Biology, and Scientific Inquiry Inquiring About Life Concept 1.1 The study of life reveals unifying themes Theme: New Properties Emerge at Successive Levels of Biological Organization Theme: Life's Processes Involve the Expression and Transmission of Genetic Information Theme: Life Requires the Transfer and Transformation of Energy and Matter Theme: From Molecules to Ecosystems, Interactions Are Important in Biological Systems Concept 1.2 The Core Theme: Evolution accounts for the unity and diversity of life Classifying the Diversity of Life Charles Darwin and the Theory of Natural Selection The Tree of Life Concept 1.3 In studying nature, scientists make observations and form and test hypotheses Exploration and Observation Forming and Testing Hypotheses The Flexibility of the Scientific Process A Case Study in Scientific Inquiry: Investigating Coat Coloration in Mouse Populations Experimental Variables and Controls Theories in Science Concept 1.4 Science benefits from a cooperative approach and diverse viewpoints Building on the Work of Others Science, Technology, and Society The Value of Diverse Viewpoints in Science Unit 1 The Chemistry of Life Interview: Lovell Jones 2 The Chemical Context of Life A Chemical Connection to Biology Concept 2.1 Matter consists of chemical elements in pure form and in combinations called compounds Elements and Compounds The Elements of Life Case Study: Evolution of Tolerance to Toxic Elements Concept 2.2 An element's properties depend on the structure of its atoms Subatomic Particles Atomic Number and Atomic Mass Isotopes The Energy Levels of Electrons Electron Distribution and Chemical Properties Electron Orbitals Concept 2.3 The formation and function of molecules depend on chemical bonding between atoms Covalent Bonds Ionic Bonds Weak Chemical Interactions Molecular Shape and Function Concept 2.4 Chemical reactions make and break chemical bonds 3 Water and Life The Molecule That Supports All of Life Concept 3.1 Polar covalent bonds in water molecules result in hydrogen bonding Concept 3.2 Four emergent properties of water contribute to Earth's suitability for life Cohesion of Water Molecules Moderation of Temperature by Water Floating of Ice on Liquid Water Water: The Solvent of Life Possible Evolution of Life on Other Planets Concept 3.3 Acidic and basic conditionsaffect living organisms Acids and Bases The pH Scale Buffers Acidification: A Threat to Our Oceans 4 Carbon and the Molecular Diversity of Life Carbon: The Backbone of Life Concept 4.1 Organic chemistry is the study of carbon compounds Organic Molecules and the Origin of Life on Earth Concept 4.2 Carbon atoms can form diverse molecules by bonding to four other atoms The Formation of Bonds with Carbon Molecular Diversity Arising from Variation in Carbon Skeletons Concept 4.3 A few chemical groups are key to molecular function The Chemical Groups Most Important in the Processes of Life ATP: An Important Source of Energy for Cellular Processes The Chemical Elements of Life: A Review 5 The Structure and Function of Large Biological Molecules The Molecules of Life Concept 5.1 Macromolecules are polymers, built from monomers The Synthesis and Breakdown of Polymers The Diversity of Polymers Concept 5.2 Carbohydrates serve as fuel and building material Sugars Polysaccharides Concept 5.3 Lipids are a diverse group of hydrophobic molecules Fats Phospholipids Steroids Concept 5.4 Proteins include a diversity of structures, resulting in a wide range of functions Amino Acid Monomers Polypeptides (Amino Acid Polymers) Protein Structure and Function Concept 5.5 Nucleic acids store, transmit, and help express hereditary information The Roles of Nucleic Acids The Components of Nucleic Acids Nucleotide Polymers The Structures of DNA and RNA Molecules Concept 5.6 Genomics and proteomics have transformed biological inquiry and applications DNA and Proteins as Tape Measures of Evolution Unit 2 The Cell Interview: Elba Serrano 6 A Tour of the Cell The Fundamental Units of Life Concept 6.1 Biologists use microscopes and biochemistry to study cells Microscopy Cell Fractionation Concept 6.2 Eukaryotic cells have internal membranes that compartmentalize their functions Comparing Prokaryotic and Eukaryotic Cells A Panoramic View of the Eukaryotic Cell Concept 6.3 The eukaryotic cell's genetic instructions are housed in the nucleus and carried out by the ribosomes The Nucleus: Information Central Ribosomes: Protein Factories Concept 6.4 The endomembrane system regulates protein traffic and performs metabolic functions The Endoplasmic Reticulum: Biosynthetic Factory The Golgi Apparatus: Shipping and Receiving Center Lysosomes: Digestive Compartments Vacuoles: Diverse Maintenance Compartments The Endomembrane System: A Review Concept 6.5 Mitochondria and chloroplasts change energy from one form to another The Evolutionary Origins of Mitochondria and Chloroplasts Mitochondria: Chemical Energy Conversion Chloroplasts: Capture of Light Energy Peroxisomes: Oxidation Concept 6.6 The cytoskeleton is a network of fibers that organizes structures and activities in the cell Roles of the Cytoskeleton: Support and Motility Components of the Cytoskeleton Concept 6.7 Extracellular components and connections between cells help coordinate cellular activities Cell Walls of Plants The Extracellular Matrix (ECM) of Animal Cells Cell Junctions Concept 6.8 A cell is greater than the sum of its parts 7 Membrane Structure and Function Life at the Edge Concept 7.1 Cellular membranes are fluid mosaics of lipids and proteins The Fluidity of Membranes Evolution of Differences in Membrane Lipid Composition Membrane Proteins and Their Functions The Role of Membrane Carbohydrates in Cell-Cell Recognition Synthesis and Sidedness of Membranes Concept 7.2 Membrane structure results in selective permeability The Permeability of the Lipid Bilayer Transport Proteins Concept 7.3 Passive transport is diffusion of a substance across a membrane with no energy investment Effects of Osmosis on Water Balance Facilitated Diffusion: Passive Transport Aided by Proteins Concept 7.4 Active transport uses energy to move solutes against their gradients The Need for Energy in Active Transport How Ion Pumps Maintain Membrane Potential Cotransport: Coupled Transport by a Membrane Protein Concept 7.5 Bulk transport across the plasma membrane occurs by exocytosis and endocytosis Exocytosis Endocytosis 8 An Introduction to Metabolism The Energy of Life Concept 8.1 An organism's metabolism transforms matter and energy, subject to the laws of thermodynamics Organization of the Chemistry of Life into Metabolic Pathways Forms of Energy The Laws of Energy Transformation Concept 8.2 The free-energy change of a reaction tells us whether or not the reaction occurs spontaneously Free-Energy Change, DG Free Energy, Stability, and Equilibrium Free Energy and Metabolism Concept 8.3 ATP powers cellular work by coupling exergonic reactions to endergonic reactions The Structure and Hydrolysis of ATP How the Hydrolysis of ATP Performs Work The Regeneration of ATP Concept 8.4 Enzymes speed up metabolic reactions by lowering energy barriers The Activation Energy Barrier How Enzymes Speed Up Reactions Substrate Specificity of Enzymes Catalysis in the Enzyme's Active Site Effects of Local Conditions on Enzyme Activity The Evolution of Enzymes Concept 8.5 Regulation of enzyme activity helps control metabolism Allosteric Regulation of Enzymes Localization of Enzymes Within the Cell 9 Cellular Respiration and Fermentation Life Is Work Concept 9.1 Catabolic pathways yield energy by oxidizing organic fuels Catabolic Pathways and Production of ATP Redox Reactions: Oxidation and Reduction The Stages of Cellular Respiration: A Preview Concept 9.2 Glycolysis harvests chemical energy by oxidizing glucose to pyruvate Concept 9.3 After pyruvate is oxidized, the citric acid cycle completes the energy-yielding oxidation of organic molecules Oxidation of Pyruvate to Acetyl CoA The Citric Acid Cycle Concept 9.4 During oxidative phosphorylation, chemiosmosis couples electron transport to ATP synthesis The Pathway of Electron Transport Chemiosmosis: The Energy-Coupling Mechanism An Accounting of ATP Production by Cellular Respiration Concept 9.5 Fermentation and anaerobic respirationenable cells to produce ATP without the use of oxygen Types of Fermentation Comparing Fermentation with Anaerobic and Aerobic Respiration The Evolutionary Significance of Glycolysis Concept 9.6 Glycolysis and the citric acid cycle connect to many other metabolic pathways The Versatility of Catabolism Biosynthesis (Anabolic Pathways) Regulation of Cellular Respiration via Feedback Mechanisms 10 Photosynthesis The Process That Feeds the Biosphere Concept 10.1 Photosynthesis converts light energy to the chemical energy of food Chloroplasts: The Sites of Photosynthesis in Plants Tracking Atoms Through Photosynthesis: Scientific Inquiry The Two Stages of Photosynthesis: A Preview Concept 10.2 The light reactions convert solar energy to the chemical energy of ATP and NADPH The Nature of Sunlight Photosynthetic Pigments: The Light Receptors Excitation of Chlorophyll by Light A Photosystem: A Reaction-Center Complex Associated with Light-Harvesting Complexes Linear Electron Flow Cyclic Electron Flow A Comparison of Chemiosmosis in Chloroplasts and Mitochondria Concept 10.3 The Calvin cycle uses the chemical energy of ATP and NADPH to reduce CO2 to sugar Concept 10.4 Alternative mechanisms of carbon fixation have evolved in hot, arid climates Photorespiration: An Evolutionary Relic?

C4 Plants CAM Plants Concept 10.5 Life depends on photosynthesis The Importance of Photosynthesis: A Review 11 Cell Communication Cellular Messaging Concept 11.1 External signals are converted to responses within the cell Evolution of Cell Signaling Local and Long-Distance Signaling The Three Stages of Cell Signaling: A Preview Concept 11.2 Reception: A signaling molecule binds to a receptor protein, causing it to change shape Receptors in the Plasma Membrane Intracellular Receptors Concept 11.3 Transduction: Cascades of molecular interactions relay signals from receptors to target molecules in the cell Signal Transduction Pathways Protein Phosphorylation and Dephosphorylation Small Molecules and Ions as Second Messengers Concept 11.4 Response: Cell signaling leads to regulation of transcription or cytoplasmic activities Nuclear and Cytoplasmic Responses Regulation of the Response Concept 11.5 Apoptosis integrates multiple cell-signaling pathways Apoptosis in the Soil Worm Caenorhabditis elegans Apoptotic Pathways and the Signals That Trigger Them 12 The Cell Cycle The Key Roles of Cell Division Concept 12.1 Most cell division results in genetically identical daughter cells Cellular Organization of the Genetic Material Distribution of Chromosomes During Eukaryotic Cell Division Concept 12.2 The mitotic phase alternates with interphase in the cell cycle Phases of the Cell Cycle The Mitotic Spindle: A Closer Look Cytokinesis: A Closer Look Binary Fission in Bacteria The Evolution of Mitosis Concept 12.3 The eukaryotic cell cycle is regulated by a molecular control system The Cell Cycle Control System Loss of Cell Cycle Controls in Cancer Cells Unit 3 Genetics Interview: Shirley Tilghman 13 Meiosis and Sexual Life Cycles Variations on a Theme Concept 13.1 Offspring acquire genes from parents by inheriting chromosomes Inheritance of Genes Comparison of Asexual and Sexual Reproduction Concept 13.2 Fertilization and meiosis alternate in sexual life cycles Sets of Chromosomes in Human Cells Behavior of Chromosome Sets in the Human Life Cycle The Variety of Sexual Life Cycles Concept 13.3 Meiosis reduces the number of chromosome sets from diploid to haploid The Stages of Meiosis Crossing Over and Synapsis During Prophase I A Comparison of Mitosis and Meiosis Concept 13.4 Genetic variation produced in sexual life cycles contributes to evolution Origins of Genetic Variation Among Offspring The Evolutionary Significance of Genetic Variation Within Populations 14 Mendel and the Gene Idea Drawing from the Deck of Genes Concept 14.1 Mendel used the scientific approach to identify two laws of inheritance Mendel's Experimental, Quantitative Approach The Law of Segregation The Law of Independent Assortment Concept 14.2 Probability laws govern Mendelian inheritance The Multiplication and Addition Rules Applied to Monohybrid Crosses Solving Complex Genetics Problems with the Rules of Probability Concept 14.3 Inheritance patterns are often more complex than predicted by simple Mendelian genetics Extending Mendelian Genetics for a Single Gene Extending Mendelian Genetics for Two or More Genes Nature and Nurture: The Environmental Impact on Phenotype A Mendelian View of Heredity and Variation Concept 14.4 Many human traits follow Mendelian patterns of inheritance Pedigree Analysis Recessively Inherited Disorders Dominantly Inherited Disorders Multifactorial Disorders Genetic Testing and Counseling 15 The Chromosomal Basis of Inheritance Locating Genes Along Chromosomes Concept 15.1 Morgan showed that Mendelian inheritance has its physical basis in the behavior of chromosomes: scientific inquiry Morgan's Choice of Experimental Organism Correlating Behavior of a Gene's Alleles with Behavior of a Chromosome Pair Concept 15.2 Sex-linked genes exhibit unique patterns of inheritance The Chromosomal Basis of Sex Inheritance of X-Linked Genes X Inactivation in Female Mammals Concept 15.3 Linked genes tend to be inherited together because they are located near each other on the same chromosome How Linkage Affects Inheritance Genetic Recombination and Linkage Mapping the Distance Between Genes Using Recombination Data: Scientific Inquiry Concept 15.4 Alterations of chromosome number or structure cause some genetic disorders Abnormal Chromosome Number Alterations of Chromosome Structure Human Disorders Due to Chromosomal Alterations Concept 15.5 Some inheritance patterns are exceptions to standard Mendelian inheritance Genomic Imprinting Inheritance of Organelle Genes 16 The Molecular Basis of Inheritance Life's Operating Instructions Concept 16.1 DNA is the genetic material The Search for the Genetic Material: Scientific Inquiry Building a Structural Model of DNA: Scientific Inquiry Concept 16.2 Many proteins work together in DNA replication and repair The Basic Principle: Base Pairing to a Template Strand DNA Replication: A Closer Look Proofreading and Repairing DNA Evolutionary Significance of Altered DNA Nucleotides Replicating the Ends of DNA Molecules Concept 16.3 A chromosome consists of a DNA molecule packed together with proteins 17 Gene Expression: From Gene to Protein The Flow of Genetic Information Concept 17.1 Genes specify proteins via transcription and translation Evidence from Studying Metabolic Defects Basic Principles of Transcription and Translation The Genetic Code Concept 17.2 Transcription is the DNA-directed synthesis of RNA: a closer look Molecular Components of Transcription Synthesis of an RNA Transcript Concept 17.3 Eukaryotic cells modify RNA after transcription Alteration of mRNA Ends Split Genes and RNA Splicing Concept 17.4 Translation is the RNA-directed synthesis of a polypeptide: a closer look Molecular Components of Translation Building a Polypeptide Completing and Targeting the Functional Protein Making Multiple Polypeptides in Bacteria and Eukaryotes Concept 17.5 Mutations of one or a few nucleotides can affect protein structure and function Types of Small-Scale Mutations New Mutations and Mutagens What Is a Gene?

Revisiting the Question 18 Regulation of Gene Expression Beauty in the Eye of the Beholder Concept 18.1 Bacteria often respond to environmental change by regulating transcription Operons: The Basic Concept Repressible and Inducible Operons: Two Types of Negative Gene Regulation Positive Gene Regulation Concept 18.2 Eukaryotic gene expression is regulated at many stages Differential Gene Expression Regulation of Chromatin Structure Regulation of Transcription Initiation Mechanisms of Post-Transcriptional Regulation Concept 18.3 Noncoding RNAs play multiple roles in controlling gene expression Effects on mRNAs by MicroRNAs and Small Interfering RNAs Chromatin Remodeling and Effects on Transcription by ncRNAs The Evolutionary Significance of Small ncRNAs Concept 18.4 A program of differential gene expression leads to the different cell types in a multicellular organism A Genetic Program for Embryonic Development Cytoplasmic Determinants and Inductive Signals Sequential Regulation of Gene Expression During Cellular Differentiation Pattern Formation: Setting Up the Body Plan Concept 18.5 Cancer results from genetic changes that affect cell cycle control Types of Genes Associated with Cancer Interference with Normal Cell-Signaling Pathways The Multistep Model of Cancer Development Inherited Predisposition and Environmental Factors Contributing to Cancer The Role of Viruses in Cancer 19 Viruses A Borrowed Life Concept 19.1 A virus consists of a nucleic acid surrounded by a protein coat The Discovery of Viruses: Scientific Inquiry Structure of Viruses Concept 19.2 Viruses replicate only in host cells General Features of Viral Replicative Cycles Replicative Cycles of Phages Replicative Cycles of Animal Viruses Evolution of Viruses Concept 19.3 Viruses and prions are formidable pathogens in animals and plants Viral Diseases in Animals Emerging Viruses Viral Diseases in Plants Prions: Proteins as Infectious Agents 20 DNA Tools and Biotechnology The DNA Toolbox Concept 20.1 DNA sequencing and DNA cloning are valuable tools for genetic engineering and biological inquiry DNA Sequencing Making Multiple Copies of a Gene or Other DNA Segment Using Restriction Enzymes to Make a Recombinant DNA Plasmid Amplifying DNA: The Polymerase Chain Reaction (PCR) and Its Use in DNA Cloning Expressing Cloned Eukaryotic Genes Concept 20.2 Biologists use DNA technology to study gene expression and function Analyzing Gene Expression Determining Gene Function Concept 20.3 Cloned organisms and stem cells are useful for basic research and other applications Cloning Plants: Single-Cell Cultures Cloning Animals: Nuclear Transplantation Stem Cells of Animals Concept 20.4 The practical applications of DNA-based biotechnology affect our lives in many ways Medical Applications Forensic Evidence and Genetic Profiles Environmental Cleanup Agricultural Applications Safety and Ethical Questions Raised by DNA Technology 21 Genomes and Their Evolution Reading the Leaves from the Tree of Life Concept 21.1 The Human Genome Project fostered development of faster, less expensive sequencing techniques Concept 21.2 Scientists use bioinformatics to analyze genomes and their functions Centralized Resources for Analyzing Genome Sequences Identifying Protein-Coding Genes and Understanding Their Functions Understanding Genes and Gene Expression at the Systems Level Concept 21.3 Genomes vary in size, number of genes, and gene density Genome Size Number of Genes Gene Density and Noncoding DNA Concept 21.4 Multicellular eukaryotes have a lot of noncoding DNA and many multigene families Transposable Elements and Related Sequences Other Repetitive DNA, Including Simple Sequence DNA Genes and Multigene Families Concept 21.5 Duplication, rearrangement, and mutation of DNA contribute to genome evolution Duplication of Entire Chromosome Sets Alterations of Chromosome Structure Duplication and Divergence of Gene-Sized Regions of DNA Rearrangements of Parts of Genes: Exon Duplication and Exon Shuffling How Transposable Elements Contribute to Genome Evolution Concept 21.6 Comparing genome sequences provides clues to evolution and development Comparing Genomes Widespread Conservation of Developmental Genes Among Animals Unit 4 Mechanisms of Evolution Interview: Jack Szostak 22 Descent with Modification: A Darwinian View of Life Endless Forms Most Beautiful Concept 22.1 The Darwinian revolution challenged traditional views of a young Earth inhabited by unchanging species Scala Naturae and Classification of Species Ideas About Change over Time Lamarck's Hypothesis of Evolution Concept 22.2 Descent with modification by natural selection explains the adaptations of organisms and the unity and diversity of life Darwin's Research Ideas from The Origin of Species Key Features of Natural Selection Concept 22.3 Evolution is supported by an overwhelming amount of scientific evidence Direct Observations of Evolutionary Change Homology The Fossil Record Biogeography What Is Theoretical About Darwin's View of Life?

23 The Evolution of Populations The Smallest Unit of Evolution Concept 23.1 Genetic variation makes evolution possible Genetic Variation Sources of Genetic Variation Concept 23.2 The Hardy-Weinberg equation can be used to test whether a population is evolving Gene Pools and Allele Frequencies The Hardy-Weinberg Equation Concept 23.3 Natural selection, genetic drift, and gene flow can alter allele frequencies in a population Natural Selection Genetic Drift Case Study: Impact of Genetic Drift on the Greater Prairie Chicken Effects of Genetic Drift: A Summary Gene Flow Concept 23.4 Natural selection is the only mechanism that consistently causes adaptive evolution Natural Selection: A Closer Look The Key Role of Natural Selection in Adaptive Evolution Sexual Selection Balancing Selection Why Natural Selection Cannot Fashion Perfect Organisms 24 The Origin of Species That "Mystery of Mysteries" Concept 24.1 The biological species concept emphasizes reproductive isolation The Biological Species Concept Other Definitions of Species Concept 24.2 Speciation can take place with or without geographic separation Allopatric ("Other Country") Speciation Sympatric ("Same Country") Speciation Allopatric and Sympatric Speciation: A Review Concept 24.3 Hybrid zones reveal factors that cause reproductive isolation Patterns Within Hybrid Zones Hybrid Zones and Environmental Change Hybrid Zones over Time Concept 24.4 Speciation can occur rapidly or slowly and can result from changes in few or many genes The Time Course of Speciation Studying the Genetics of Speciation From Speciation to Macroevolution 25 The History of Life on Earth A Surprise in the Desert Concept 25.1 Conditions on early Earth made the origin of life possible Synthesis of Organic Compounds on Early Earth Abiotic Synthesis of Macromolecules Protocells Self-Replicating RNA Concept 25.2 The fossil record documents the history of life The Fossil Record How Rocks and Fossils Are Dated The Origin of New Groups of Organisms Concept 25.3 Key events in life's history include the origins of unicellular and multicellular organisms and the colonization of land The First Single-Celled Organisms The Origin of Multicellularity The Colonization of Land Concept 25.4 The rise and fall of groups of organisms reflect differences in speciation and extinction rates Plate Tectonics Mass Extinctions Adaptive Radiations Concept 25.5 Major changes in body form can result from changes in the sequences and regulation of developmental genes Effects of Developmental Genes The Evolution of Development Concept 25.6 Evolution is not goal oriented Evolutionary Novelties Evolutionary Trends Unit 5 The Evolutionary History of Biological Diversity Interview: Nancy Moran 26 Phylogeny and the Tree of Life Investigating the Tree of Life Concept 26.1 Phylogenies show evolutionary relationships Binomial Nomenclature Hierarchical Classification Linking Classification and Phylogeny What We Can and Cannot Learn from Phylogenetic Trees Applying Phylogenies Concept 26.2 Phylogenies are inferred from morphological and molecular data Morphological and Molecular Homologies Sorting Homology from Analogy Evaluating Molecular Homologies Concept 26.3 Shared characters are used to construct phylogenetic trees Cladistics Phylogenetic Trees with Proportional Branch Lengths Maximum Parsimony and Maximum Likelihood Phylogenetic Trees as Hypotheses Concept 26.4 An organism's evolutionary history is documented in its genome Gene Duplications and Gene Families Genome Evolution Concept 26.5 Molecular clocks help track evolutionary time Molecular Clocks Applying a Molecular Clock: Dating the Origin of Hiv Concept 26.6 Our understanding of the tree of life continues to change based on new data From Two Kingdoms to Three Domains The Important Role of Horizontal Gene Transfer 27 Bacteria and Archaea Masters of Adaptation Concept 27.1 Structural and functional adaptations contribute to prokaryotic success Cell-Surface Structures Motility Internal Organization and DNA Reproduction Concept 27.2 Rapid reproduction, mutation, and genetic recombination promote genetic diversity in prokaryotes Rapid Reproduction and Mutation Genetic Recombination Concept 27.3 Diverse nutritional and metabolic adaptations have evolved in prokaryotes The Role of Oxygen in Metabolism Nitrogen Metabolism Metabolic Cooperation Concept 27.4 Prokaryotes have radiated into a diverse set of lineages An Overview of Prokaryotic Diversity Bacteria Archaea Concept 27.5 Prokaryotes play crucial roles in the biosphere Chemical Recycling Ecological Interactions Concept 27.6 Prokaryotes have both beneficial and harmful impacts on humans Mutualistic Bacteria Pathogenic Bacteria Prokaryotes in Research and Technology 28 Protists Living Small Concept 28.1 Most eukaryotes are single-celled organisms Structural and Functional Diversity in Protists Four Supergroups of Eukaryotes Endosymbiosis in Eukaryotic Evolution Concept 28.2 Excavates include protists with modified mitochondria and protists with unique flagella Diplomonads and Parabasalids Euglenozoans Concept 28.3 SAR is a highly diverse group of protists defined by DNA similarities Stramenopiles Alveolates Rhizarians Concept 28.4 Red algae and green algae are the closest relatives of plants Red Algae Green Algae Concept 28.5 Unikonts include protists that are closely related to fungi and animals Amoebozoans Opisthokonts Concept 28.6 Protists play key roles in ecological communities Symbiotic Protists Photosynthetic Protists 29 Plant Diversity I: How Plants Colonized Land The Greening of Earth Concept 29.1 Plants evolved from green algae Morphological and Molecular Evidence Adaptations Enabling the Move to Land Derived Traits of Plants The Origin and Diversification of Plants Concept 29.2 Mosses and other nonvascular plants have life cycles dominated by gametophytes Bryophyte Gametophytes Bryophyte Sporophytes The Ecological and Economic Importance of Mosses Concept 29.3 Ferns and other seedless vascular plants were the first plants to grow tall Origins and Traits of Vascular Plants Classification of Seedless Vascular Plants The Significance of Seedless Vascular Plants 30 Plant Diversity Ii: the Evolution of Seed Plants Transforming the World Concept 30.1 Seeds and pollen grains are key adaptations for life on land Advantages of Reduced Gametophytes Heterospory: The Rule Among Seed Plants Ovules and Production of Eggs Pollen and Production of Sperm The Evolutionary Advantage of Seeds Concept 30.2 Gymnosperms bear "naked" seeds, typically on cones The Life Cycle of a Pine Early Seed Plants and the Rise of Gymnosperms Gymnosperm Diversity Concept 30.3 The reproductive adaptations of angiosperms include flowers and fruits Characteristics of Angiosperms Angiosperm Evolution Angiosperm Diversity Concept 30.4 Human welfare depends on seed plants Products from Seed Plants Threats to Plant Diversity 31 Fungi Hidden Networks Concept 31.1 Fungi are heterotrophs that feed by absorption Nutrition and Ecology Body Structure Specialized Hyphae in Mycorrhizal Fungi Concept 31.2 Fungi produce spores through sexual or asexual life cycles Sexual Reproduction Asexual Reproduction Concept 31.3 The ancestor of fungi was an aquatic, single-celled, flagellated protist The Origin of Fungi Basal Fungal Groups The Move to Land Concept 31.4 Fungi have radiated into a diverse set of lineages Chytrids Zygomycetes Glomeromycetes Ascomycetes Basidiomycetes Concept 31.5 Fungi play key roles in nutrient cycling, ecological interactions, and human welfare Fungi as Decomposers Fungi as Mutualists Fungi as Parasites Practical Uses of Fungi 32 An Overview of Animal Diversity A Kingdom of Consumers Concept 32.1 Animals are multicellular, heterotrophic eukaryotes with tissues that develop from embryonic layers Nutritional Mode Cell Structure and Specialization Reproduction and Development Concept 32.2 The history of animals spans more than half a billion years Steps in the Origin of Multicellular Animals Neoproterozoic Era (1 Billion-541 Million Years Ago) Paleozoic Era (541-252 Million Years Ago) Mesozoic Era (252-66 Million Years Ago) Cenozoic Era (66 Million Years Ago to the Present) Concept 32.3 Animals can be characterized by "body plans" Symmetry Tissues Body Cavities Protostome and Deuterostome Development Concept 32.4 Views of animal phylogeny continue to be shaped by new molecular and morphological data The Diversification of Animals Future Directions in Animal Systematics 33 An Introduction to Invertebrates A Dragon Without a Backbone Concept 33.1 Sponges are basal animals that lack tissues Concept 33.2 Cnidarians are an ancient phylum of eumetazoans Medusozoans Anthozoans Concept 33.3 Lophotrochozoans, a clade identified by molecular data, have the widest range of animal body forms Flatworms Rotifers and Acanthocephalans Lophophorates: Ectoprocts and Brachiopods Molluscs Annelids Concept 33.4 Ecdysozoans are the most species-rich animal group Nematodes Arthropods Concept 33.5 Echinoderms and chordates are deuterostomes Echinoderms Chordates 34 The Origin and Evolution of Vertebrates Half a Billion Years of Backbones Concept 34.1 Chordates have a notochord and a dorsal, hollow nerve cord Derived Characters of Chordates Lancelets Tunicates Early Chordate Evolution Concept 34.2 Vertebrates are chordates that have a backbone Derived Characters of Vertebrates Hagfishes and Lampreys Early Vertebrate Evolution Concept 34.3 Gnathostomes are vertebrates that have jaws Derived Characters of Gnathostomes Fossil Gnathostomes Chondrichthyans (Sharks, Rays, and Their Relatives) Ray-Finned Fishes and Lobe-Fins Concept 34.4 Tetrapods are gnathostomes that have limbs Derived Characters of Tetrapods The Origin of Tetrapods Amphibians Concept 34.5 Amniotes are tetrapods that have a terrestrially adapted egg Derived Characters of Amniotes Early Amniotes Reptiles Concept 34.6 Mammals are amniotes that have hair and produce milk Derived Characters of Mammals Early Evolution of Mammals Monotremes Marsupials Eutherians (Placental Mammals) Concept 34.7 Humans are mammals that have a large brain and bipedal locomotion Derived Characters of Humans The Earliest Hominins Australopiths Bipedalism Tool Use Neanderthals Concept 35.1 Plants have a hierarchical organization consisting of organs, tissues, and cells Basic Vascular Plant Organs: Roots, Stems, and Leaves Dermal, Vascular, and Ground Tissues Common Types of Plant Cells Concept 35.2 Different meristems generate new cells for primary and secondary growth Concept 35.3 Primary growth lengthens roots and shoots Primary Growth of Roots Primary Growth of Shoots Concept 35.4 Secondary growth increases the diameter of stems and roots in woody plants The Vascular Cambium and Secondary Vascular Tissue The Cork Cambium and the Production of Periderm Evolution of Secondary Growth Concept 35.5 Growth, morphogenesis, and cell differentiation produce the plant body Model Organisms: Revolutionizing the Study of Plants Growth: Cell Division and Cell Expansion Morphogenesis and Pattern Formation Gene Expression and the Control of Cell Differentiation Shifts in Development: Phase Changes Genetic Control of Flowering 36 Resource Acquisition and Transport in Vascular Plants A Whole Lot of Shaking Going On Concept 36.1 Adaptations for acquiring resources were key steps in the evolution of vascular plants Shoot Architecture and Light Capture Root Architecture and Acquisition of Water and Minerals Concept 36.2 Different mechanisms transport substances over short or long distances The Apoplast and Symplast: Transport Continuums Short-Distance Transport of Solutes Across Plasma Membranes Short-Distance Transport of Water Across Plasma Membranes Long-Distance Transport: The Role of Bulk Flow Concept 36.3 Transpiration drives the transport of water and minerals from roots to shoots via the xylem Absorption of Water and Minerals by Root Cells Transport of Water and Minerals into the Xylem Bulk Flow Transport Via the Xylem Xylem Sap Ascent by Bulk Flow: A Review Concept 36.4 The rate of transpiration is regulated by stomata Stomata: Major Pathways for Water Loss Mechanisms of Stomatal Opening and Closing Stimuli for Stomatal Opening and Closing Effects of Transpiration on Wilting and Leaf Temperature Adaptations That Reduce Evaporative Water Loss Concept 36.5 Sugars are transported from sources to sinks via the phloem Movement from Sugar Sources to Sugar Sinks Bulk Flow by Positive Pressure: The Mechanism of Translocation in Angiosperms Concept 36.6 The symplast is highly dynamic Changes in Plasmodesmatal Number and Pore Size Phloem: An Information Superhighway Electrical Signaling in the Phloem 37 Soil and Plant Nutrition The Corkscrew Carnivore Concept 37.1 Soil contains a living, complex ecosystem Soil Texture Topsoil Composition Soil Conservation and Sustainable Agriculture Concept 37.2 Plant roots absorb essential elements from the soil Essential Elements Symptoms of Mineral Deficiency Improving Plant Nutrition by Genetic Modification Concept 37.3 Plant nutrition often involves relationships with other organisms Bacteria and Plant Nutrition Fungi and Plant Nutrition Epiphytes, Parasitic Plants, and Carnivorous Plants 38 Angiosperm Reproduction and Biotechnology Flowers of Deceit Concept 38.1 Flowers, double fertilization, and fruits are key features of the angiosperm life cycle Flower Structure and Function Methods of Pollination The Angiosperm Life Cycle: An Overview Seed Development and Structure: A Closer Look Sporophyte Development from Seed to Mature Plant Fruit Structure and Function Concept 38.2 Flowering plants reproduce sexually, asexually, or both Mechanisms of Asexual Reproduction Advantages and Disadvantages of Asexual and Sexual Reproduction Mechanisms That Prevent Self-Fertilization Totipotency, Vegetative Reproduction, and Tissue Culture Concept 38.3 People modify crops by breeding and genetic engineering Plant Breeding Plant Biotechnology and Genetic Engineering The Debate over Plant Biotechnology 39 Plant Responses to Internal and External Signals Stimuli and a Stationary Life Concept 39.1 Signal transduction pathways link signal reception to response Reception Transduction Response Concept 39.2 Plant hormones help coordinate growth, development, and responses to stimuli A Survey of Plant Hormones Concept 39.3 Responses to light are critical for plant success Blue-Light Photoreceptors Phytochrome Photoreceptors Biological Clocks and Circadian Rhythms The Effect of Light on the Biological Clock Photoperiodism and Responses to Seasons Concept 39.4 Plants respond to a wide variety of stimuli other than light Gravity Mechanical Stimuli Environmental Stresses Concept 39.5 Plants respond to attacks by pathogens and herbivores Defenses Against Pathogens Defenses Against Herbivores Unit 7 Animal Form and Function Interview: Harald zur Hausen 40 Basic Principles of Animal Form and Function Diverse Forms, Common Challenges Concept 40.1 Animal form and function are correlated at all levels of organization Evolution of Animal Size and Shape Exchange with the Environment Hierarchical Organization of Body Plans Coordination and Control Concept 40.2 Feedback control maintains the internal environment in many animals Regulating and Conforming Homeostasis Concept 40.3 Homeostatic processes for thermoregulation involve form, function, and behavior Endothermy and Ectothermy Variation in Body Temperature Balancing Heat Loss and Gain Acclimatization in Thermoregulation Physiological Thermostats and Fever Concept 40.4 Energy requirements are related to animal size, activity, and environment Energy Allocation and Use Quantifying Energy Use Minimum Metabolic Rate and Thermoregulation Influences on Metabolic Rate Torpor and Energy Conservation 41 Animal Nutrition The Need to Feed Concept 41.1 An animal's diet must supply chemical energy, organic building blocks, and essential nutrients Essential Nutrients Dietary Deficiencies Assessing Nutritional Needs Concept 41.2 Food processing involves ingestion, digestion, absorption, and elimination Digestive Compartments Concept 41.3 Organs specialized for sequential stages of food processing form the mammalian digestive system The Oral Cavity, Pharynx, and Esophagus Digestion in the Stomach Digestion in the Small Intestine Absorption in the Small Intestine Processing in the Large Intestine Concept 41.4 Evolutionary adaptations of vertebrate digestive systems correlate with diet Dental Adaptations Stomach and Intestinal Adaptations Mutualistic Adaptations Concept 41.5 Feedback circuits regulate digestion, energy storage, and appetite Regulation of Digestion Regulation of Energy Storage Regulation of Appetite and Consumption 42 Circulation and Gas Exchange Trading Places Concept 42.1 Circulatory systems link exchange surfaces with cells throughout the body Gastrovascular Cavities Open and Closed Circulatory Systems Organization of Vertebrate Circulatory Systems Concept 42.2 Coordinated cycles of heart contraction drive double circulation in mammals Mammalian Circulation The Mammalian Heart: A Closer Look Maintaining the Heart's Rhythmic Beat Concept 42.3 Patterns of blood pressure and flow reflect the structure and arrangement of blood vessels Blood Vessel Structure and Function Blood Flow Velocity Blood Pressure Capillary Function Fluid Return by the Lymphatic System Concept 42.4 Blood components function in exchange, transport, and defense Blood Composition and Function Cardiovascular Disease Concept 42.5 Gas exchange occurs across specialized respiratory surfaces Partial Pressure Gradients in Gas Exchange Respiratory Media Respiratory Surfaces Gills in Aquatic Animals Tracheal Systems in Insects Lungs Concept 42.6 Breathing ventilates the lungs How an Amphibian Breathes How a Bird Breathes How a Mammal Breathes Control of Breathing in Humans Concept 42.7 Adaptations for gas exchange include pigments that bind and transport gases Coordination of Circulation and Gas Exchange Respiratory Pigments Respiratory Adaptations of Diving Mammals 43 The Immune System Recognition and Response Concept 43.1 In innate immunity, recognition and response rely on traits common to groups of pathogens Innate Immunity of Invertebrates Innate Immunity of Vertebrates Evasion of Innate Immunity by Pathogens Concept 43.2 In adaptive immunity, receptors provide pathogen-specific recognition Antigen Recognition by B Cells and Antibodies Antigen Recognition by T Cells B Cell and T Cell Development Concept 43.3 Adaptive immunity defends against infection of body fluids and body cells Helper T Cells: Activating Adaptive Immunity B Cells and Antibodies: A Response to Extracellular Pathogens Cytotoxic T Cells: A Response to Infected Host Cells Summary of the Humoral and Cell-Mediated Immune Responses Immunization Active and Passive Immunity Antibodies as Tools Immune Rejection Concept 43.4 Disruptions in immune system function can elicit or exacerbate disease Exaggerated, Self-Directed, and Diminished Immune Responses Evolutionary Adaptations of Pathogens That Underlie Immune System Avoidance Cancer and Immunity 44 Osmoregulation and Excretion A Balancing Act Concept 44.1 Osmoregulation balances the uptake and loss of water and solutes Osmosis and Osmolarity Osmoregulatory Challenges and Mechanisms Energetics of Osmoregulation Transport Epithelia in Osmoregulation Concept 44.2 An animal's nitrogenous wastes reflect its phylogeny and habitat Forms of Nitrogenous Waste The Influence of Evolution and Environment on Nitrogenous Wastes Concept 44.3 Diverse excretory systems are variations on a tubular theme Excretory Processes Survey of Excretory Systems Concept 44.4 The nephron is organized for stepwise processing of blood filtrate From Blood Filtrate to Urine: A Closer Look Solute Gradients and Water Conservation Adaptations of the Vertebrate Kidney to Diverse Environments Concept 44.5 Hormonal circuits link kidney function, water balance, and blood pressure Homeostatic Regulation of the Kidney 45 Hormones and the Endocrine System The Body's Long-Distance Regulators Concept 45.1 Hormones and other signaling molecules bind to target receptors, triggering specific response pathways Intercellular Communication Chemical Classes of Local Regulators and Hormones Cellular Hormone Response Pathways Endocrine Tissues and Organs Concept 45.2 Feedback regulation and coordination with the nervous system are common in hormone pathways Simple Endocrine Pathways Simple Neuroendocrine Pathways Feedback Regulation Coordination of the Endocrine and Nervous Systems Thyroid Regulation: A Hormone Cascade Pathway Hormonal Regulation of Growth Concept 45.3 Endocrine glands respond to diverse stimuli in regulating homeostasis, development, and behavior Parathyroid Hormone and Vitamin D: Control of Blood Calcium Adrenal Hormones: Response to Stress Sex Hormones Hormones and Biological Rhythms Evolution of Hormone Function 46 Animal Reproduction Let Me Count the Ways Concept 46.1 Both asexual and sexual reproduction occur in the animal kingdom Mechanisms of Asexual Reproduction Variation in Patterns of Sexual Reproduction Reproductive Cycles Sexual Reproduction: An Evolutionary Enigma Concept 46.2 Fertilization depends on mechanisms that bring together sperm and eggs of the same species Ensuring the Survival of Offspring Gamete Production and Delivery Concept 46.3 Reproductive organs produce and transport gametes Human Male Reproductive Anatomy Human Female Reproductive Anatomy Gametogenesis Concept 46.4 The interplay of tropic and sex hormones regulates reproduction in mammals Hormonal Control of the Male Reproductive System Hormonal Control of Female Reproductive Cycles Human Sexual Response Concept 46.5 In placental mammals, an embryo develops fully within the mother's uterus Conception, Embryonic Development, and Birth Maternal Immune Tolerance of the Embryo and Fetus Contraception and Abortion Modern Reproductive Technologies 47 Animal Development A Body-Building Plan Concept 47.1 Fertilization and cleavage initiate embryonic development Fertilization Cleavage Concept 47.2 Morphogenesis in animals involves specific changes in cell shape, position, and survival Gastrulation Developmental Adaptations of Amniotes Organogenesis The Cytoskeleton in Morphogenesis Concept 47.3 Cytoplasmic determinants and inductive signals regulate cell fate Fate Mapping Axis Formation Restricting Developmental Potential Cell Fate Determination and Pattern Formation by Inductive Signals Cilia and Cell Fate 48 Neurons, Synapses, and Signaling Lines of Communication Concept 48.1 Neuron structure and organization reflect function in information transfer Neuron Structure and Function Introduction to Information Processing Concept 48.2 Ion pumps and ion channels establish the resting potential of a neuron Formation of the Resting Potential Modeling the Resting Potential Concept 48.3 Action potentials are the signals conducted by axons Hyperpolarization and Depolarization Graded Potentials and Action Potentials Generation of Action Potentials: A Closer Look Conduction of Action Potentials Concept 48.4 Neurons communicate with other cells at synapses Generation of Postsynaptic Potentials Summation of Postsynaptic Potentials Termination of Neurotransmitter Signaling Modulated Signaling at Synapses Neurotransmitters 49 Nervous Systems Command and Control Center Concept 49.1 Nervous systems consist of circuits of neurons and supporting cells Glia Organization of the Vertebrate Nervous System The Peripheral Nervous System Concept 49.2 The vertebrate brain is regionally specialized Arousal and Sleep Biological Clock Regulation Emotions Functional Imaging of the Brain Concept 49.3 The cerebral cortex controls voluntary movement and cognitive functions Information Processing Language and Speech Lateralization of Cortical Function Frontal Lobe Function Evolution of Cognition in Vertebrates Concept 49.4 Changes in synaptic connections underlie memory and learning Neuronal Plasticity Memory and Learning Long-Term Potentiation Concept 49.5 Many nervous system disorders can now be explained in molecular terms Schizophrenia Depression The Brain's Reward System and Drug Addiction Alzheimer's Disease Parkinson's Disease Future Directions 50 Sensory and Motor Mechanisms Sense and Sensibility Concept 50.1 Sensory receptors transduce stimulus energy and transmit signals to the central nervous system Sensory Reception and Transduction Transmission Perception Amplification and Adaptation Types of Sensory Receptors Concept 50.2 In hearing and equilibrium, mechanoreceptors detect moving fluid or settling particles Sensing of Gravity and Sound in Invertebrates Hearing and Equilibrium in Mammals Hearing and Equilibrium in Other Vertebrates Concept 50.3 The diverse visual receptors of animals depend on light-absorbing pigments Evolution of Visual Perception The Vertebrate Visual System Concept 50.4 The senses of taste and smell rely on similar sets of sensory receptors Taste in Mammals Smell in Humans Concept 50.5 The physical interaction of protein filaments is required for muscle function Vertebrate Skeletal Muscle Other Types of Muscle Concept 50.6 Skeletal systems transform muscle contraction into locomotion Types of Skeletal Systems Types of Locomotion 51 Animal Behavior The How and Why of Animal Activity Concept 51.1 Discrete sensory inputs can stimulate both simple and complex behaviors Fixed Action Patterns Migration Behavioral Rhythms Animal Signals and Communication Concept 51.2 Learning establishes specific links between experience and behavior Experience and Behavior Learning Concept 51.3 Selection for individual survival and reproductive success can explain diverse behaviors Evolution of Foraging Behavior Mating Behavior and Mate Choice Concept 51.4 Genetic analyses and the concept of inclusive fitness provide a basis for studying the evolution of behavior Genetic Basis of Behavior Genetic Variation and the Evolution of Behavior Altruism Inclusive Fitness Evolution and Human Culture Unit 8 Ecology Interview: Tracy Langkilde 52 An Introduction to Ecology and the Biosphere Discovering Ecology Concept 52.1 Earth's climate varies by latitude and season and is changing rapidly Global Climate Patterns Regional and Local Effects on Climate Microclimate Global Climate Change Concept 52.2 The distribution of terrestrial biomes is controlled by climate and disturbance Climate and Terrestrial Biomes General Features of Terrestrial Biomes Disturbance and Terrestrial Biomes Concept 52.3 Aquatic biomes are diverse and dynamicsystems that cover most of Earth Zonation in Aquatic Biomes Concept 52.4 Interactions between organisms and the environment limit the distribution of species Dispersal and Distribution Biotic Factors Abiotic Factors Concept 52.5 Ecological change and evolution affect one another over long and short periods of time 53 Population Ecology Turtle Tracks Concept 53.1 Biotic and abiotic factors affect population density, dispersion, and demographics Density and Dispersion Demographics Concept 53.2 The exponential model describes population growth in an idealized, unlimited environment Changes in Population Size Exponential Growth Concept 53.3 The logistic model describes how a population grows more slowly as it nears its carrying capacity The Logistic Growth Model The Logistic Model and Real Populations Concept 53.4 Life history traits are products of natural selection Diversity of Life Histories "Trade-offs" and Life Histories Concept 53.5 Density-dependent factors regulate population growth Population Change and Population Density Mechanisms of Density-Dependent Population Regulation Population Dynamics Population Cycles: Scientific Inquiry Concept 53.6 The human population is no longer growing exponentially but is still increasing rapidly The Global Human Population Global Carrying Capacity 54 Community Ecology Communities in Motion Concept 54.1 Community interactions are classified by whether they help, harm, or have no effect on the species involved Competition Exploitation Positive Interactions Concept 54.2 Diversity and trophic structure characterize biological communities Species Diversity Diversity and Community Stability Trophic Structure Species with a Large Impact Bottom-Up and Top-Down Controls Concept 54.3 Disturbance influences species diversity and composition Characterizing Disturbance Ecological Succession Human Disturbance Concept 54.4 Biogeographic factors affect community diversity Latitudinal Gradients Area Effects Island Equilibrium Model Concept 54.5 Pathogens alter community structure locally and globally Pathogens and Community Structure Community Ecology and Zoonotic Diseases 55 Ecosystems and Restoration Ecology Transformed to Tundra Concept 55.1 Physical laws govern energy flow and chemical cycling in ecosystems Conservation of Energy Conservation of Mass Energy, Mass, and Trophic Levels Concept 55.2 Energy and other limiting factors control primary production in ecosystems Ecosystem Energy Budgets Primary Production in Aquatic Ecosystems Primary Production in Terrestrial Ecosystems Concept 55.3 Energy transfer between trophic levels is typically only 10% efficient Production Efficiency Trophic Efficiency and Ecological Pyramids Concept 55.4 Biological and geochemical processes cycle nutrients and water in ecosystems Decomposition and Nutrient Cycling Rates Biogeochemical Cycles Case Study: Nutrient Cycling in the Hubbard Brook Experimental Forest Concept 55.5 Restoration ecologists return degraded ecosystems to a more natural state Bioremediation Biological Augmentation Ecosystems: A Review 56 Conservation Biology and Global Change Psychedelic Treasure Concept 56.1 Human activities threaten Earth's biodiversity Three Levels of Biodiversity Biodiversity and Human Welfare Threats to Biodiversity Concept 56.2 Population conservation focuses on population size, genetic diversity, and critical habitat Small-Population Approach Declining-Population Approach Weighing Conflicting Demands Concept 56.3 Landscape and regional conservationhelp sustain biodiversity Landscape Structure and Biodiversity Establishing Protected Areas Urban Ecology Concept 56.4 Earth is changing rapidly as a result of human actions Nutrient Enrichment Toxins in the Environment Greenhouse Gases and Climate Change Depletion of Atmospheric Ozone Concept 56.5 Sustainable development can improve human lives while conserving biodiversity Sustainable Development The Future of the Biosphere